Cheap flights from Mcallen to Knoxville

Compare Mcallen to Knoxville flight deals

Find the cheapest month or even day of the year to fly to Knoxville

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Flight deals from Mcallen to Knoxville

Looking for a cheap last-minute deal or the best round-trip flight from Mcallen Airport to Knoxville Airport? If you want to travel next month, round-trip fares start from $395. Find the lowest prices on one-way and round-trip tickets right here.

Knoxville.$397 per passenger.Departing Mon, Aug 3, returning Thu, Aug 6.Round-trip flight with Allegiant Air.Outbound indirect flight with Allegiant Air, departing from Mcallen on Mon, Aug 3, arriving in Knoxville.Inbound indirect flight with Allegiant Air, departing from Knoxville on Thu, Aug 6, arriving in Mcallen.Price includes taxes and charges.From $397, select.

Knoxville.$449 per passenger.Departing Sat, Jul 18, returning Thu, Jul 23.Round-trip flight with Allegiant Air.Outbound indirect flight with Allegiant Air, departing from Mcallen on Sat, Jul 18, arriving in Knoxville.Inbound indirect flight with Allegiant Air, departing from Knoxville on Thu, Jul 23, arriving in Mcallen.Price includes taxes and charges.From $449, select.

Knoxville.$993 per passenger.Departing Fri, Oct 30, returning Mon, Nov 2.Round-trip flight with United.Outbound indirect flight with United, departing from Mcallen on Fri, Oct 30, arriving in Knoxville.Inbound indirect flight with United, departing from Knoxville on Mon, Nov 2, arriving in Mcallen.Price includes taxes and charges.From $993, select.

Find the cheapest month to fly from Mcallen to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Mcallen to Knoxville flights are currently cheapest in August.

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Mcallen to Knoxville: Alternative routes

Compare routes from Mcallen to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Knoxville

18km from central Knoxville

ClosestCheapest

from $395

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Mcallen to Knoxville: Flight information

The things to know before you go.

Cheapest flight found	$397
Cheapest month to fly	August

Finding cheap flights from Mcallen to Knoxville: Frequently asked questions

How much are round-trip flights from Mcallen to Knoxville?

The best price we found for a round-trip flight from Mcallen to Knoxville is $395. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Mcallen to Knoxville?

Currently, there are no airlines that fly direct from Mcallen to Knoxville. But we found flights with one or more stops from $397.

How many flights are there a week from Mcallen to Knoxville?

There are no flights flying from Mcallen to Knoxville, as of July 2026.

When is the cheapest time to fly from Mcallen to Knoxville?

The cheapest month to fly from Mcallen to Knoxville is usually August.

Which upcoming date is cheapest to fly from Mcallen Airport to Knoxville Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Mcallen Airport to Knoxville Airport on Monday, August 3, 2026.

Can I get a direct flight from Mcallen Airport to Knoxville Airport?

No airlines currently offer direct flights between Mcallen Airport and Knoxville Airport. Most routes have one or more stops.

How can I find the best flight deal to Knoxville?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Knoxville?

We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly with from Mcallen Airport to Knoxville?

Currently, Allegiant Air offers the cheapest flight tickets to Knoxville.

Traveling from Mcallen Airport (MFE) to Knoxville Airport (TYS): what you need to know

Your MFE to TYS flight won't wait if you're late, so get to the airport on time. Arrive up to one hour in advance for domestic flights and two hours ahead when you're flying internationally.
Flying during a peak time like July? Public holidays and other high seasons can mean longer lines at airport checkpoints. Play things extra safe and get there up to four hours ahead of international flights and two hours before a domestic departure.
Think about adding a stopover when booking your ticket from Mcallen Airport to Knoxville Airport. Simply uncheck 'Direct flights only' to break up your journey, or perhaps explore a new destination along the way. Check out these options between MFE and TYS:
- Dallas Fort Worth International Airport
- Houston George Bush Intercntl. Airport
- Orlando Sanford Airport

How to find the cheapest flights from Mcallen Airport (MFE) to Knoxville Airport (TYS)

The lowest price we've found for a one-way Mcallen Airport to Knoxville Airport flight is $194. A round-trip ticket is currently $395. Depending on the availability when you book, these fares could change.
Don't leave everything to the last moment. You're more likely to find cheap tickets from MFE to TYS if you book ahead. Airlines often offer some excellent early bird discounts.
The 'Whole month' tool shows you the cheapest flights from Mcallen Airport to Knoxville Airport across every month. It's an easy way to find a bargain if your plans aren't set in stone.
You won't have to check back in every day to see if fares have dropped when you set up a Price Alert. We'll update you as soon as there's a change in price on cheap flights from MFE to TYS.
Tailor your trip using filters. Select your ideal departure and arrival times, total journey duration and airlines. You can also sort your results by 'Best,' 'Cheapest' or 'Fastest' flights from Mcallen Airport to Knoxville Airport.

Handy information about Mcallen Airport (MFE)

The address for MFE is 2500 S Bicentenial Blvd.
Mcallen Airport has a strong on-time record, so you're less likely to experience disruptions. Departures from MFE land at their destination as scheduled 82% of the time.
Mcallen Airport is about 8 kilometers from central Mcallen. If you're driving, catching a cab or ride-sharing from the center, it'll take you 10 minutes or so to arrive, depending on the traffic.
Planning to take public transport? Expect a journey time of around 25 minutes.
Get your vacation off to a relaxed start by staying near MFE. Whether you have an early flight from Mcallen Airport to Knoxville Airport or just don't want to be rushed, these stays have you covered:

Arriving at Knoxville Airport (TYS)

If you're getting in on a late Mcallen Airport to Knoxville Airport flight, nothing tops the convenience of staying near the terminal. Grab your suitcases from the carousel and then be showered and resting not long after at one of these accommodation options near TYS:
Get your adventure underway by picking up a Knoxville Airport rental car. Grab a set of wheels from Budget, Alamo or Avis and experience the lesser-explored corners of Knoxville and beyond.
Booking your vehicle from Knoxville Airport around three weeks in advance can help you get the lowest rate.

Getting from Knoxville Airport (TYS) to central Knoxville

You'll find TYS at 2055 Alcoa Highway.
From Knoxville Airport, Knoxville is approximately 24 kilometers away. It takes around 25 minutes to reach the center by car.
If you're using public transport, expect a journey of about 50 minutes.

When to fly to Knoxville Airport (TYS)

It's time to plan your dates for your flight from Mcallen Airport to Knoxville Airport. October is the most popular month to visit Knoxville. If you want a more low-key vibe, go in March.
When reserving your flight from Mcallen Airport to Knoxville Airport, think about the type of weather you enjoy. July is the warmest month in Knoxville, with the temperature ranging from 17ºC (63ºF) to 32ºC (90ºF).
Search for cheap tickets from MFE to TYS in January if you like cooler conditions. Temperatures are at their lowest around then, ranging between -6ºC (21ºF) and 11ºC (52ºF) on average.

Explore more of the United States

Knoxville has plenty going for it, but there are so many other parts of the United States just waiting to be discovered. About 451 kilometers north of Knoxville, a visit to Columbus will keep your itinerary busy. Start with leading sights like Franklin Park Conservatory and Botanical Gardens, Whetstone Park / Park of Roses and Ohio Theater.
Indianapolis is another standout destination in the United States and is around 467 kilometers north-west of Knoxville. No trip is complete without seeing Lucas Oil Stadium, Eiteljorg Museum and The Children's Museum of Indianapolis.