Cheap flights from Milwaukee General Mitchell to Knoxville

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Compare Milwaukee General Mitchell to Knoxville flight deals

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Flight deals from Milwaukee General Mitchell to Knoxville

Looking for a cheap last-minute deal or the best round-trip flight from Milwaukee General Mitchell Airport to Knoxville Airport? If you want to travel next month, round-trip fares start from $278. Find the lowest prices on one-way and round-trip tickets right here.

Knoxville.$268 per passenger.Departing Wed, Sep 16, returning Thu, Sep 17.Round-trip flight with United.Outbound indirect flight with United, departing from Milwaukee General Mitchell on Wed, Sep 16, arriving in Knoxville.Inbound indirect flight with United, departing from Knoxville on Thu, Sep 17, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $268, select.

Knoxville.$278 per passenger.Departing Fri, Aug 7, returning Thu, Aug 13.Round-trip flight with United.Outbound indirect flight with United, departing from Milwaukee General Mitchell on Fri, Aug 7, arriving in Knoxville.Inbound indirect flight with United, departing from Knoxville on Thu, Aug 13, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $278, select.

Knoxville.$288 per passenger.Departing Sun, Jan 17, returning Fri, Jan 22.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Milwaukee General Mitchell on Sun, Jan 17, arriving in Knoxville.Inbound indirect flight with Delta, departing from Knoxville on Fri, Jan 22, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $288, select.

Knoxville.$294 per passenger.Departing Sun, Oct 4, returning Thu, Oct 8.Round-trip flight with United.Outbound indirect flight with United, departing from Milwaukee General Mitchell on Sun, Oct 4, arriving in Knoxville.Inbound indirect flight with United, departing from Knoxville on Thu, Oct 8, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $294, select.

Knoxville.$337 per passenger.Departing Mon, Jul 20, returning Sat, Aug 1.Round-trip flight with United.Outbound indirect flight with United, departing from Milwaukee General Mitchell on Mon, Jul 20, arriving in Knoxville.Inbound indirect flight with United, departing from Knoxville on Sat, Aug 1, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $337, select.

Knoxville.$367 per passenger.Departing Sun, Jul 19, returning Sun, Jul 26.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Milwaukee General Mitchell on Sun, Jul 19, arriving in Knoxville.Inbound indirect flight with Delta, departing from Knoxville on Sun, Jul 26, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $367, select.

Find the cheapest month to fly from Milwaukee General Mitchell to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Milwaukee General Mitchell to Knoxville flights are currently cheapest in September.

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Milwaukee General Mitchell to Knoxville: Alternative routes

Compare routes from Milwaukee General Mitchell to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Knoxville

18km from central Knoxville

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from $268

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Milwaukee to Knoxville: Flight information

The things to know before you go.

Cheapest flight found	$268
Cheapest month to fly	September

Finding cheap flights from Milwaukee General Mitchell to Knoxville: Frequently asked questions

How much are round-trip flights from Milwaukee General Mitchell to Knoxville?

The best price we found for a round-trip flight from Milwaukee General Mitchell to Knoxville is $268. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Milwaukee General Mitchell to Knoxville?

Currently, there are no airlines that fly direct from Milwaukee General Mitchell to Knoxville. But we found flights with one or more stops from $268.

How many flights are there a week from Milwaukee General Mitchell to Knoxville?

There are no flights flying from Milwaukee General Mitchell to Knoxville, as of July 2026.

When is the cheapest time to fly from Milwaukee General Mitchell to Knoxville?

The cheapest month to fly from Milwaukee General Mitchell to Knoxville is usually September.

Which upcoming date is cheapest to fly from Milwaukee General Mitchell Airport to Knoxville Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Milwaukee General Mitchell Airport to Knoxville Airport on Wednesday, September 16, 2026.

Can I get a direct flight from Milwaukee General Mitchell Airport to Knoxville Airport?

No airlines currently offer direct flights between Milwaukee General Mitchell Airport and Knoxville Airport. Most routes have one or more stops.

How can I find the best flight deal to Knoxville?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Knoxville?

We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly with from Milwaukee General Mitchell Airport to Knoxville?

Currently, United offers the cheapest flight tickets to Knoxville.

Traveling from Milwaukee General Mitchell Airport (MKE) to Knoxville Airport (TYS): what you need to know

Your MKE to TYS flight won't wait if you're late, so show up at the airport on time. Arrive up to one hour in advance for domestic flights and two hours ahead when you're traveling internationally.
You can expect longer lines during popular months such as June. Arriving up to four hours ahead of international flights and two hours for a domestic departure is a smart move.
We make it a piece of cake to book a flight with a stopover. To see all your options for tickets from Milwaukee General Mitchell Airport to Knoxville Airport, uncheck 'Direct flights only.' Then, choose a flight that has a stop long enough to tour the city of your choice. Top stopovers between MKE and TYS include:
- Chicago O'Hare International Airport
- Atlanta Hartsfield-Jackson Airport
- Charlotte Douglas Airport

Handy information about Milwaukee General Mitchell Airport (MKE)

You'll find MKE at 5300 S. Howell Avenue.
Of the flights that depart from Milwaukee General Mitchell Airport, 76% arrive on time at their destination.
Milwaukee General Mitchell Airport is about 16 kilometers from central Milwaukee. If you're driving, ride-sharing or catching a cab from the center, it'll take you 20 minutes or so to arrive, depending on the traffic.
Planning to catch public transport? Expect a journey time of around 40 minutes.
Get your travels off to a hassle-free start by staying near MKE. Whether you're catching an early flight from Milwaukee General Mitchell Airport to Knoxville Airport or just don't like being rushed, these stays have you covered:

Arriving at Knoxville Airport (TYS)

If you're landing on a late Milwaukee General Mitchell Airport to Knoxville Airport flight, nothing tops the convenience of being near the terminal. Grab your suitcases from the carousel and then be showered and snoozing not long after at one of these accommodation options near TYS:
Begin your adventure by picking up a Knoxville Airport rental car. Grab your wheels from Budget, Alamo or Avis and explore beyond Knoxville's main sights.
Booking your ride from Knoxville Airport around three weeks ahead increases your chances of getting a good deal.

When to fly to Knoxville Airport (TYS)

October is the most popular month for flights from Milwaukee General Mitchell Airport to Knoxville Airport. To skip the crowds, visit Knoxville in March.
Book your flight from Milwaukee General Mitchell Airport to Knoxville Airport for July if you'd like to go to Knoxville during its warmest month. You can expect temperatures of between 17ºC (63ºF) and 32ºC (90ºF).
Look for cheap tickets from MKE to TYS in January if you like traveling in cooler conditions. Temperatures are at their lowest then, ranging between -6ºC (21ºF) and 11ºC (52ºF) on average.

Explore more of the United States

You've seen Knoxville, now it's time to discover more of the United States. Journey about 451 kilometers north to Columbus to tick off its popular sights. From Franklin Park Conservatory and Botanical Gardens to Whetstone Park / Park of Roses and Ohio Theater, you'll have a packed itinerary ahead.
If you want to check out another major stop in the United States, head for Indianapolis, about 467 kilometers north-west of Knoxville. Lucas Oil Stadium, Eiteljorg Museum and The Children's Museum of Indianapolis are the start of reasons to visit.