Cheap flights from Santa Ana John Wayne to Des Moines

Compare Santa Ana John Wayne to Des Moines flight deals

Find the cheapest month or even day of the year to fly to Des Moines

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Flight deals from Santa Ana John Wayne to Des Moines

Looking for a cheap last-minute deal or the best round-trip flight from Santa Ana John Wayne to Des Moines? Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Santa Ana John Wayne to Des Moines

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santa Ana John Wayne to Des Moines flights are currently cheapest in December.

Direct flights from Santa Ana John Wayne to Des Moines

Santa Ana John Wayne to Des Moines: Alternative routes

Compare routes from Santa Ana John Wayne to Des Moines below. You may find an airport to fly into that's cheaper, faster, or easier than Des Moines.

Santa Ana to Des Moines: Flight information

The things to know before you go.
Cheapest flight found$106
Cheapest month to flyNovember
Average flight time3 hrs, 19 mins
Most popular airlineAllegiant Air
Average flights per week4

Finding cheap flights from Santa Ana John Wayne to Des Moines: Frequently asked questions

The best price we found for a round-trip flight from Santa Ana John Wayne to Des Moines is $106. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
3 hours and 19 minutes is the average flight time from Santa Ana John Wayne to Des Moines.
Allegiant Air flies direct from Santa Ana John Wayne to Des Moines.
There are 4 flights per week flying from Santa Ana John Wayne to Des Moines, as of October 2025.
The cheapest month to fly from Santa Ana John Wayne to Des Moines is usually November.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Santa Ana John Wayne Airport to Des Moines Airport on Thursday, November 20, 2025.
Yes – the average flight time is 3 hours and 19 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Des Moines but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
Currently, Allegiant Air offers the cheapest flight tickets to Des Moines.

Flying from John Wayne Airport (SNA) to Des Moines International Airport (DSM): what you need to know

  • Around 3 hours 25 minutes is how long you'll be traveling on a direct flight from John Wayne Airport to Des Moines International Airport.

  • For a stress-free journey, turn up at the airport two hours ahead of international flights and an hour before domestic departures. This way, you'll have plenty of time to catch your SNA to DSM flight.

  • You can expect longer queues during popular months like July. Arriving up to four hours ahead of international flights and two hours for a domestic departure is a smart move.

  • Allegiant Air has direct flights from John Wayne Airport to Des Moines International Airport. Book with this popular carrier, then get ready to check out the sights in Des Moines — and maybe even more of United States if time allows.

  • Allegiant Air has the highest passenger demand on this route.

  • With 70.0% of its services landing on schedule, Allegiant Air is the most punctual carrier operating SNA to DSM flights.

  • If you want to include a stop along the way, simply deselect 'Direct flights only' when searching for your ticket from John Wayne Airport to Des Moines International Airport. Here are the top stopovers between SNA and DSM:

    • Denver International Airport

    • Phoenix Sky Harbor International Airport

    • Harry Reid Airport (formerly McCarran Airport)

How to find the cheapest flights from John Wayne Airport (SNA) to Des Moines International Airport (DSM)

  • Right now, $54 is the lowest price we've found for a one-way John Wayne Airport to Des Moines International Airport flight. The best price for a return ticket is $106. Keep in mind that fares could change due to availability at the time of booking.

  • Score cheap tickets from SNA to DSM by booking at least seven months ahead. According to our research, that's the sweet spot for bagging a bargain.

  • June is the cheapest month for flights from John Wayne Airport to Des Moines International Airport. If you'd like to travel during a different time of year, the 'Whole month' tool will show you the lowest prices for each month.

  • There's no need to check every day to see if fares have gone down when you set up a Price Alert. We'll let you know the moment there's a better deal on cheap flights from SNA to DSM.

  • Select your preferred departure and arrival times, number of stops and airlines with the filters. Or sort your results by 'Cheapest' to get the best deals on flights from John Wayne Airport to Des Moines International Airport.

Handy information about John Wayne Airport (SNA)

  • The address for SNA is 18601 Airport Way.

  • John Wayne Airport gets high marks for on-time performance. 81.53% of flights that take off from SNA reach their destination without delay.

  • Central Santa Ana to John Wayne Airport is approximately 8 kilometers. Depending on traffic, it'll take you about 15 minutes to get there if you're catching a cab, ride-sharing or driving.

  • The trip when using public transport usually takes 1 hour 5 minutes.

  • Need a convenient hotel close to SNA? If you're boarding an early flight from John Wayne Airport to Des Moines International Airport, these accommodation options will put you moments from check-in:

Arriving at Des Moines International Airport (DSM)

Getting from Des Moines International Airport (DSM) to central Des Moines

  • DSM is located at 5800 Fleur Drive, Suite 201.

  • Des Moines International Airport to the center of Des Moines has a drive time of around 15 minutes. It's approximately 10 kilometers away.

  • It typically takes 45 minutes if you're using public transport.

When to fly to Des Moines International Airport (DSM)

  • July is the busiest month for flights from John Wayne Airport to Des Moines International Airport. For smaller crowds, visit Des Moines in April.

  • The warmest month in Des Moines is July, with temperatures ranging between 15ºC (59ºF) and 31ºC (88ºF). Lock in your flights from John Wayne Airport to Des Moines International Airport in this month if this is the type of weather you like.

  • Look for cheap tickets from SNA to DSM in January if you like traveling in cooler conditions. Temperatures are at their lowest around then, ranging between -13ºC (9ºF) and 2ºC (36ºF) on average.

Explore more of United States

  • Chicago is just one of the many cities in United States waiting to be explored after you've experienced Des Moines. Around 499 kilometers away to the east, top sights here include Millennium Park, Art Institute of Chicago and LandShark Beer Garden at Navy Pier.

  • Milwaukee is another well-known destination in United States and is around 499 kilometers east of Des Moines. No trip is complete without seeing Miller Park, Pabst Mansion and Milwaukee Public Museum.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.