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Flights from Seattle to South Carolina

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Flight deals from Seattle to South Carolina

Looking for cheap flights from Seattle to South Carolina, or a last-minute trip? Find the lowest prices on one-way and round-trip flights right here.
Charleston.$175 per passenger.Departing Wed, Sep 10, returning Sat, Sep 13.Round-trip flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departing from Seattle / Tacoma International on Wed, Sep 10, arriving in Charleston.Inbound indirect flight with Southwest Airlines, departing from Charleston on Sat, Sep 13, arriving in Seattle / Tacoma International.Price includes taxes and charges.From $175, select.
Greenville.$275 per passenger.Departing Sat, Oct 25, returning Sat, Nov 1.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Seattle / Tacoma International on Sat, Oct 25, arriving in Greenville-Spartanburg.Inbound indirect flight with Delta, departing from Greenville-Spartanburg on Sat, Nov 1, arriving in Seattle / Tacoma International.Price includes taxes and charges.From $275, select.
Columbia.$277 per passenger.Departing Thu, Aug 7, returning Thu, Aug 14.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Seattle / Tacoma International on Thu, Aug 7, arriving in Columbia Metropolitan.Inbound indirect flight with Delta, departing from Columbia Metropolitan on Thu, Aug 14, arriving in Seattle / Tacoma International.Price includes taxes and charges.From $277, select.
Myrtle Beach.$400 per passenger.Departing Fri, Aug 8, returning Fri, Aug 15.Round-trip flight with Alaska Airlines and Spirit Airlines.Outbound indirect flight with Alaska Airlines, departing from Seattle / Tacoma International on Fri, Aug 8, arriving in Myrtle Beach International.Inbound indirect flight with Spirit Airlines, departing from Myrtle Beach International on Fri, Aug 15, arriving in Seattle / Tacoma International.Price includes taxes and charges.From $400, select.

Flying from Seattle to South Carolina

Arm yourself with these facts on the fly.
Cheapest flight found$175, Charleston
Cheapest month to flySeptember
Average flight time5 hrs, 17 mins
Cheapest airport to fly fromSeattle / Tacoma International
Most popular airlineHawaiian Airlines

Frequently asked questions

We looked at all of the upcoming round-trip flights from Seattle to South Carolina we could find over the next 12 months. It looks like $175 is the best price. This is good, compared to the average South Carolina ticket price of $434.
The cheapest month to fly from Seattle to Charleston Airport is usually September. The cheapest month to fly from Seattle to Myrtle Beach International Airport is usually August. The cheapest month to fly from Seattle to Columbia Metropolitan Airport is usually August. And the cheapest month to fly from Seattle to Greenville-Spartanburg Airport is usually October.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Seattle to South Carolina on Wednesday, September 10, 2025.
Seattle / Tacoma International Airport offers direct flights to South Carolina.
If you're flying from Seattle, the cheapest city in South Carolina to fly into is Charleston. The cheapest airport serving Charleston at the moment is Charleston.
The average flight time between Seattle and South Carolina is 5 hours and 17 minutes.