Cheap flights from Panama City to Chicago

Compare Panama City to Chicago flight deals

Find the cheapest month or even day of the year to fly to Chicago

Book the best Chicago fare with no extra fees

Flight deals from Panama City to Chicago

Looking for a cheap last-minute deal or the best round-trip flight from Panama City to Chicago? Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Panama City to Chicago

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Chicago flights are currently cheapest in November.

Direct flights from Panama City to Chicago

Alternative Panama City to Chicago routes

Looking for the cheapest, fastest or easiest route from Panama City to Chicago? You could fly into the following airports instead.

Panama City to Chicago: Flight information

The things to know before you go.
Cheapest flight found$390
Cheapest month to flyFebruary
Average flight time5 hrs, 41 mins
Most popular airlineCopa
Average flights per week42

Finding cheap flights from Panama City to Chicago: Frequently asked questions

There are 4 airports in Chicago: Chicago Midway, Chicago O'Hare International, Chicago Dupage County, and Chicago Rockford.
The best price we found for a round-trip flight from Panama City to Chicago is $390. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
5 hours and 41 minutes is the average flight time from Panama City to Chicago.
Copa, United and EVA Air fly direct from Panama City to Chicago.
There are 42 flights per week flying from Panama City to Chicago, as of October 2024.
The cheapest month to fly from Panama City to Chicago is usually October 2024.
If you're flying from Panama City, the cheapest airport near Chicago is Chicago O'Hare International – which is 25.4 km away from the center of Chicago. We've found flights to this airport from $390.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Chicago on Thursday, February 27, 2025.
Yes – the average flight time is 5 hours and 41 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Chicago but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Chicago is around 40 days in advance, so don’t leave your flight to the last minute.
In October, the average temperature is usually around 11°C. July is typically the warmest month in Chicago, when it usually averages around 26°C. You can expect the least rain in January. The coldest month is January, with temperatures averaging -8°C. The rainiest month is August.
The cheapest airline that flies to Chicago is Avianca, and the cheapest airline that flies to Chicago O'Hare International Airport is Copa.

How to find cheap flights from Panama City to Chicago

Looking for a cheap flight from Panama City to Chicago? Whether you are flying one-way or return, here are a few tips on how to score the best price and make your flight journey as smooth as possible.

  • Simply hit 'search'. We've compared flights from all major airlines and online travel agents to find the cheapest flight tickets from Panama City to Chicago. And with us there are no hidden fees - what you see is what you pay.

  • Flex your dates to secure the best fares for your Panama City to Chicago flight. If your travel dates are flexible, use Skyscanner's 'Whole month' tool to find the cheapest month, and even day to fly from Panama City to Chicago from your chosen departure location.

  • Set up a Price Alert. We price check with over 1000 travel companies so you don't have to. You can easily track the price of your airline tickets from Panama City to Chicago by creating an alert. Whenever prices go down or up, you'll get an email or push notification to help make sure you get the best possible flight deal.

  • Look for direct flights. Only interested in direct flights from Panama City to Chicago? Make sure to tick 'Non-stop flights only' when performing a search. If there are direct Panama City to Chicago flights available, these will appear in the results.

  • Find the cheapest Business class flights from Panama City to Chicago Check the difference in price of your plane ticket from Panama City to Chicago when travelling in Economy, Premium economy, Business or First class. Note that not all cabin classes are available for every destination or airline.

  • Include nearby airports in your search. Widen your search for Panama City to Chicago flight deals by selecting the "add nearby airports" option. This will allow you to see flight prices for all the nearest airports at your departure and destination point and could help you save money.

  • Search for flights on the go. To get the best flight booking experience on the go, download our app and search for cheap flight tickets from Panama City to Chicago when out and about.

Book a flight from Panama City to Chicago with extra peace of mind

  • Find flexible flights from Panama City to Chicago. Your airline might be offering flexible air tickets from Panama City to Chicago which means you won't lose out if your flight has to be changed or canceled.

  • Add travel cost protection. Avoid travel pitfalls and choose travel cost protection - it's available at the checkout as you book your flight from Panama City to Chicago with us.

  • Reduce your carbon footprint by selecting a greener Panama City to Chicago flight option. To check whether there are any lower emissions flights available on your route, simply check the “only show flights with lower CO₂ emissions” box which will be available once you have moved on from this page.

Combine your flight from Panama City to Chicago with hotels and car hire

Once you've secured your plane ticket we will also help you discover the best prices and exclusive rates for hotels in Chicago or close by. Compare hundreds of car hire companies in one go so that you get the best car hire deals for your trip.

Compare Panama City to Chicago air tickets with other destinations using the everywhere search

Not entirely set on flying to Panama City to Chicago yet? You can easily browse other destinations by searching flights to 'Everywhere' - this will allow you to find the cheapest place to travel from your origin.


Prices shown on this page are estimated lowest prices only. Found in the last 45 days.