Skyscanner

Cheap flights from Syracuse to St Louis

Travelers and cabin class

Compare Syracuse to St Louis flight deals

Find the cheapest month or even day of the year to fly to St Louis

Book the best St Louis fare with no extra fees

Flight deals from Syracuse to St Louis

Looking for a cheap last-minute deal or the best round-trip flight from Syracuse to St Louis? Find the lowest prices on one-way and round-trip tickets right here.
St Louis.$245 per passenger.Departing Fri, Jun 13, returning Sun, Jun 22.Round-trip flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departing from Syracuse on Fri, Jun 13, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departing from St Louis on Sun, Jun 22, arriving in Syracuse.Price includes taxes and charges.From $245, select.
St Louis.$249 per passenger.Departing Wed, Jul 16, returning Tue, Jul 22.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Syracuse on Wed, Jul 16, arriving in St Louis.Inbound indirect flight with Delta, departing from St Louis on Tue, Jul 22, arriving in Syracuse.Price includes taxes and charges.From $249, select.
St Louis.$250 per passenger.Departing Sat, Sep 13, returning Sun, Sep 14.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Syracuse on Sat, Sep 13, arriving in St Louis.Inbound indirect flight with Delta, departing from St Louis on Sun, Sep 14, arriving in Syracuse.Price includes taxes and charges.From $250, select.
St Louis.$274 per passenger.Departing Thu, Aug 7, returning Mon, Aug 11.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Syracuse on Thu, Aug 7, arriving in St Louis.Inbound indirect flight with Delta, departing from St Louis on Mon, Aug 11, arriving in Syracuse.Price includes taxes and charges.From $274, select.
St Louis.$413 per passenger.Departing Mon, Jun 30, returning Wed, Jul 2.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Syracuse on Mon, Jun 30, arriving in St Louis.Inbound indirect flight with Delta, departing from St Louis on Wed, Jul 2, arriving in Syracuse.Price includes taxes and charges.From $413, select.
St Louis.$443 per passenger.Departing Mon, Nov 3, returning Wed, Nov 5.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Syracuse on Mon, Nov 3, arriving in St Louis.Inbound indirect flight with Delta, departing from St Louis on Wed, Nov 5, arriving in Syracuse.Price includes taxes and charges.From $443, select.
St Louis.$443 per passenger.Departing Mon, Oct 6, returning Wed, Oct 8.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Syracuse on Mon, Oct 6, arriving in St Louis.Inbound indirect flight with Delta, departing from St Louis on Wed, Oct 8, arriving in Syracuse.Price includes taxes and charges.From $443, select.
St Louis.$443 per passenger.Departing Mon, Mar 9, returning Wed, Mar 11.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Syracuse on Mon, Mar 9, arriving in St Louis.Inbound indirect flight with Delta, departing from St Louis on Wed, Mar 11, arriving in Syracuse.Price includes taxes and charges.From $443, select.

Find the cheapest month to fly from Syracuse to St Louis

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Syracuse to St Louis flights are currently cheapest in June.
Jun
from $245
Jul
from $249
Aug
from $274
Sep
from $250
Oct
from $443
Nov
from $443
Dec
from $443
Jan
from $443
Feb
from $443
Mar
from $443
Apr
from $473
May
Find prices

Syracuse to St Louis: Alternative routes

Compare routes from Syracuse to St Louis below. You may find an airport to fly into that's cheaper, faster, or easier than St Louis.

Syracuse to St Louis: Flight information

The things to know before you go.
Cheapest flight found$245
Cheapest month to flyJune

Finding cheap flights from Syracuse to St Louis: Frequently asked questions

The best price we found for a round-trip flight from Syracuse to St Louis is $245. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Syracuse to St Louis. But we found flights with one or more stops from $245.
There are no flights flying from Syracuse to St Louis, as of June 2025.
The cheapest month to fly from Syracuse to St Louis is usually June 2025.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Syracuse Airport to St Louis Airport on Friday, June 13, 2025.
No airlines currently offer direct flights between Syracuse Airport and St Louis Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to St Louis but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to St Louis is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Frontier Airlines offers the cheapest flight tickets to St Louis.

Flying from Hancock International Airport (SYR) to Lambert-St. Louis International Airport (STL): what you need to know

  • The timezone in St Louis is UTC-5, which is one hour behind Syracuse.

  • Get to the airport on time so you don't miss your SYR to STL flight. Be there at least two hours ahead for international flights and an hour early for domestic departures to prevent a last-minute sprint to your gate.

  • Traveling during a peak month such as July? Public holidays and other popular periods can lead to longer lines at security. Play it safe and get there up to four hours before international flights and two hours before a domestic departure.

  • Consider adding a stopover when booking your ticket from Hancock International Airport to Lambert-St. Louis International Airport. Just uncheck 'Direct flights only' to break up your trip, or maybe even explore a new city along the way. Here are some options between SYR and STL:

    • O'Hare International Airport

    • Detroit Metropolitan Wayne County Airport

    • Ronald Reagan National Airport

How to find the cheapest flights from Hancock International Airport (SYR) to Lambert-St. Louis International Airport (STL)

  • $136 is currently the best price for a one-way Hancock International Airport to Lambert-St. Louis International Airport flight. Return flights start from $245. These prices may change based on availability and demand.

  • Don't leave things to the last moment. You're more likely to find cheap tickets from SYR to STL if you book early. Airlines often offer some great early bird deals.

  • If you're willing to be flexible with your travel dates, use the 'Whole month' search tool. It'll show you the cheapest price in every month when looking for your flight from Hancock International Airport to Lambert-St. Louis International Airport.

  • Spend less time searching for cheap flights from SYR to STL by setting up a Price Alert. We'll send you an email or notification through the app when a new discounted fare appears.

  • Find the ideal flight for you by using the filters. To see the 'Fastest,' 'Cheapest' or 'Best' flights from Hancock International Airport to Lambert-St. Louis International Airport, use the 'Sort by' tool. You can also filter by departure and arrival times, airline, and journey duration.

Handy information about Hancock International Airport (SYR)

  • SYR is located at City Hall.

  • 72.76% of flights departing from Hancock International Airport make it to their destination on time.

  • To reach Hancock International Airport from central Syracuse, it'll take around 25 minutes if you're traveling by car. Of course, this depends on traffic. It's approximately 18 kilometers from the airport to the city center.

  • You can expect a journey time of around 1 hour 10 minutes when using public transport.

  • Catching an early flight from Hancock International Airport to Lambert-St. Louis International Airport? Avoid the hassle of rushing to the terminal (and get some extra shut-eye) by picking one of these hotels close to SYR:

Arriving at Lambert-St. Louis International Airport (STL)

Getting from Lambert-St. Louis International Airport (STL) to central St Louis

  • You'll find STL at 10701 Lambert International Blvd..

  • Lambert-St. Louis International Airport to the center of St Louis has a drive time of around 20 minutes. It's approximately 26 kilometers away.

  • If you're traveling by public transport, expect a journey of roughly 35 minutes.

When to fly to Lambert-St. Louis International Airport (STL)

  • The quietest month for a flight from Hancock International Airport to Lambert-St. Louis International Airport is April, while July is the busiest. Pick the best time to visit St Louis based on whether you prefer a more relaxed vibe or a faster pace.

  • Lock in your flight from Hancock International Airport to Lambert-St. Louis International Airport for July if you want to go to St Louis during its warmest month. You can expect temperatures of between 17ºC (63ºF) and 33ºC (91ºF).

  • For cooler conditions, search for a cheap ticket from SYR to STL in January. Average temperatures are between -8ºC (18ºF) and 7ºC (45ºF) then.

Explore more of United States

  • You've seen St Louis, now it's time to explore other parts of United States. Journey about 418 kilometers north-east to Chicago to tick off its must-visit sights. From Millennium Park to Art Institute of Chicago and LandShark Beer Garden at Navy Pier, your itinerary will be busy.

  • If you're ready to explore another major stop in United States, consider Indianapolis, roughly 370 kilometers east of St Louis. The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo are among its highlights.

Plan the rest of your trip from Syracuse to St Louis

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.