Cheap Flights from San Diego to Palermo

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Flight deals from San Diego to Palermo

Looking for a cheap last-minute deal or the best round-trip flight from San Diego to Palermo Airport? If you want to travel next month, round-trip fares start from $945. Find the lowest prices on one-way and round-trip tickets right here.

Palermo.$781 per passenger.Departing Tue, Aug 11, returning Thu, Aug 27.Round-trip flight with SWISS and Lufthansa.Outbound indirect flight with SWISS, departing from San Diego International on Tue, Aug 11, arriving in Palermo.Inbound indirect flight with Lufthansa, departing from Palermo on Thu, Aug 27, arriving in San Diego International.Price includes taxes and charges.From $781, select.

Palermo.$917 per passenger.Departing Tue, Sep 15, returning Tue, Sep 22.Round-trip flight with Lufthansa and Ryanair.Outbound indirect flight with Lufthansa, departing from San Diego International on Tue, Sep 15, arriving in Palermo.Inbound indirect flight with Ryanair, departing from Palermo on Tue, Sep 22, arriving in San Diego International.Price includes taxes and charges.From $917, select.

Palermo.$923 per passenger.Departing Mon, Sep 14, returning Thu, Oct 8.Round-trip flight with SWISS and Lufthansa.Outbound indirect flight with SWISS, departing from San Diego International on Mon, Sep 14, arriving in Palermo.Inbound indirect flight with Lufthansa, departing from Palermo on Thu, Oct 8, arriving in San Diego International.Price includes taxes and charges.From $923, select.

Palermo.$942 per passenger.Departing Sun, May 17, returning Sun, May 24.Round-trip flight with Lufthansa and easyJet.Outbound indirect flight with Lufthansa, departing from San Diego International on Sun, May 17, arriving in Palermo.Inbound indirect flight with easyJet, departing from Palermo on Sun, May 24, arriving in San Diego International.Price includes taxes and charges.From $942, select.

Palermo.$944 per passenger.Departing Wed, Oct 7, returning Wed, Oct 21.Round-trip flight with Alaska Airlines and Ryanair.Outbound indirect flight with Alaska Airlines, departing from San Diego International on Wed, Oct 7, arriving in Palermo.Inbound indirect flight with Ryanair, departing from Palermo on Wed, Oct 21, arriving in San Diego International.Price includes taxes and charges.From $944, select.

Palermo.$945 per passenger.Departing Tue, Jun 2, returning Fri, Jun 12.Round-trip flight with WestJet and Ryanair.Outbound indirect flight with WestJet, departing from San Diego International on Tue, Jun 2, arriving in Palermo.Inbound indirect flight with Ryanair, departing from Palermo on Fri, Jun 12, arriving in San Diego International.Price includes taxes and charges.From $945, select.

Palermo.$1,113 per passenger.Departing Fri, Jun 5, returning Thu, Aug 20.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from San Diego International on Fri, Jun 5, arriving in Palermo.Inbound indirect flight with Delta, departing from Palermo on Thu, Aug 20, arriving in San Diego International.Price includes taxes and charges.From $1,113, select.

Palermo.$1,114 per passenger.Departing Wed, May 27, returning Thu, Jun 4.Round-trip flight with Alaska Airlines and Transavia France.Outbound indirect flight with Alaska Airlines, departing from San Diego International on Wed, May 27, arriving in Palermo.Inbound indirect flight with Transavia France, departing from Palermo on Thu, Jun 4, arriving in San Diego International.Price includes taxes and charges.From $1,114, select.

Palermo.$1,143 per passenger.Departing Sun, Jul 5, returning Sat, Sep 19.Round-trip flight with Lufthansa and easyJet.Outbound indirect flight with Lufthansa, departing from San Diego International on Sun, Jul 5, arriving in Palermo.Inbound indirect flight with easyJet, departing from Palermo on Sat, Sep 19, arriving in San Diego International.Price includes taxes and charges.From $1,143, select.

Palermo.$1,188 per passenger.Departing Tue, Jul 14, returning Tue, Jul 28.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from San Diego International on Tue, Jul 14, arriving in Palermo.Inbound indirect flight with Delta, departing from Palermo on Tue, Jul 28, arriving in San Diego International.Price includes taxes and charges.From $1,188, select.

Palermo.$1,223 per passenger.Departing Mon, Jun 29, returning Tue, Jul 21.Round-trip flight with Frontier Airlines and Ryanair.Outbound indirect flight with Frontier Airlines, departing from San Diego International on Mon, Jun 29, arriving in Palermo.Inbound indirect flight with Ryanair, departing from Palermo on Tue, Jul 21, arriving in San Diego International.Price includes taxes and charges.From $1,223, select.

Palermo.$1,249 per passenger.Departing Mon, Jun 15, returning Thu, Sep 17.Round-trip flight with Alaska Airlines and Wizz Air Malta.Outbound indirect flight with Alaska Airlines, departing from San Diego International on Mon, Jun 15, arriving in Palermo.Inbound indirect flight with Wizz Air Malta, departing from Palermo on Thu, Sep 17, arriving in San Diego International.Price includes taxes and charges.From $1,249, select.

Find the cheapest month to fly from San Diego to Palermo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like San Diego to Palermo flights are currently cheapest in August.

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San Diego to Palermo: Alternative routes

Compare routes from San Diego to Palermo below. You may find an airport to fly into that's cheaper, faster, or easier than Palermo.

Palermo

24km from central Palermo

ClosestCheapest

from $781

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Trapani Birgi

80km from central Palermo

from $1,313

Search flights

San Diego to Palermo: Flight information

The things to know before you go.

Cheapest flight found	$781
Cheapest month to fly	August

Finding cheap flights from San Diego to Palermo: Frequently asked questions

How much are round-trip flights from San Diego to Palermo?

The best price we found for a round-trip flight from San Diego to Palermo is $781. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from San Diego to Palermo?

Currently, there are no airlines that fly direct from San Diego to Palermo. But we found flights with one stop from $781.

How many flights are there a week from San Diego to Palermo?

There are no flights flying from San Diego to Palermo, as of May 2026.

When is the cheapest time to fly from San Diego to Palermo?

The cheapest month to fly from San Diego to Palermo is usually August.

Which upcoming date is cheapest to fly from San Diego to Palermo Airport on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from San Diego to Palermo Airport on Tuesday, August 11, 2026.

Can I get a direct flight from San Diego to Palermo Airport?

No airlines currently offer direct flights between San Diego and Palermo Airport. Most routes have one or more stops.

How can I find the best flight deal to Palermo?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Palermo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Palermo?

We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Palermo is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly with from San Diego to Palermo?

The cheapest airline that flies to Palermo is SWISS.

Flying from San Diego to Falcone-Borsellino Airport (PMO): What you need to know

San Diego International Airport (SAN) is San Diego's main airport. Explore your options for reserving a flight from San Diego to Falcone-Borsellino Airport (PMO) jetting off from here.
Palermo is eight hours ahead of San Diego. Falcone-Borsellino Airport is located in Palermo, which follows the UTC+1 timezone.
Arriving two hours before an international flight and one hour ahead of a domestic departure are tried-and-true travel tips. Show up at the airport on time to board your flight from San Diego to PMO.
With more travelers during peak seasons, aim to get to your terminal even earlier. Two hours for domestic flights and up to four for international journeys will help you deal with longer queues.

Airports in San Diego

San Diego International Airport (SAN)

Whether you're hoping to visit another city as part of your journey or just take a break, we make it easy to find a flight with a stopover. To check out your options departing from San Diego International Airport (SAN), uncheck 'Direct flights only.' London Heathrow Airport (LHR) is a stop you can make when searching for cheap flights from San Diego to PMO.
Located around 5 kilometers from central San Diego, SAN can be reached in about 10 minutes by car, depending on traffic. The journey by public transport takes roughly 20 minutes.
In search of a comfortable hotel near San Diego International Airport? If you've booked an early flight from San Diego to Falcone-Borsellino Airport, these accommodation options will have you sleeping moments from your check-in counter:
71.38% of flights leaving from San Diego International Airport land at their destination on schedule.
SAN is located at N Harbor Dr.

McClellan-Palomar Airport (CLD)

You can reach CLD from the center of San Diego in about 40 minutes by car, depending on traffic. The ride on public transport will take roughly 2 hours 15 minutes to cover the 56 kilometers or so.
Want to enjoy an extra night away before catching your San Diego to PMO flight? Unwind in a hotel near McClellan-Palomar Airport before your vacation officially begins. Here's where you can stay:

About Falcone-Borsellino Airport (PMO)

If you have a late flight from San Diego to Falcone-Borsellino Airport, nothing tops the convenience of staying near the terminal. Collect your bags from the carousel and then be showered and snoozing soon after at one of these hotels near PMO:
Pick up a Falcone-Borsellino Airport rental car and explore Palermo and beyond with your own set of wheels. ECH, U-Save and Felirent are well-known companies to choose from here.
Booking your ride around four weeks in advance of your San Diego to Falcone-Borsellino Airport flight can help you secure the lowest rate.

Getting from Falcone-Borsellino Airport (PMO) to central Palermo

The center of Palermo is around 24 kilometers from Falcone-Borsellino Airport. Journey times by car rental or cab will vary based on traffic conditions and time of day, so do a little research ahead of time.
It takes roughly 1 hour 55 minutes if you're using public transport.

How to find the cheapest flights from San Diego to Falcone-Borsellino Airport (PMO)

Currently, $404 is the best price we've found for a one-way ticket from San Diego to Falcone-Borsellino Airport. The cheapest price for a return flight is $781. Keep in mind fares may change due to availability at the time of booking.
To find cheap flights from San Diego to PMO, book in advance. Airlines usually offer lower prices when tickets first go on sale.
Affordable San Diego to Falcone-Borsellino Airport tickets are easier to find when you have flexibility in your schedule. Use the 'Whole month' search function to compare fares across each month and then fly out on the cheapest day.
Be the first to know about deals for plane tickets from San Diego to PMO by creating a Price Alert. We'll send you an email or notification on the app when a lower fare becomes available.
Save on your flight from San Diego to Falcone-Borsellino Airport by using the search filters. Choose your ideal departure time, duration and airlines, then sort the results by 'Cheapest' for the best deals.

The best time to fly from San Diego to Falcone-Borsellino Airport (PMO)

February is the quietest month for flights from San Diego to Falcone-Borsellino Airport (PMO), while August is the most popular. Choose the ideal time to visit Palermo based on whether you prefer a lively atmosphere or a more laid-back vibe.
When booking your San Diego to PMO plane ticket, consider what kind of weather works for you. August is the warmest month in Palermo, with temperatures ranging from 21ºC (70ºF) to 32ºC (90ºF).
February sees temperatures of between 6ºC (43ºF) and 16ºC (61ºF). Look for cheap tickets from San Diego to Falcone-Borsellino Airport around that time if you'd rather travel in cooler conditions.

More about Palermo

When it comes to searching for somewhere to rest your head, you'll find the best places to stay in Palermo right here. Browse these hotels after locking in your flight from San Diego to Falcone-Borsellino Airport:
There are so many things to discover in this city, it can be hard to figure out where to begin. Cathedral of Palermo, Golfo di Mondello and Spiaggia di Mondello are leading attractions which should be on any good Palermo itinerary.

Explore more of Italy

You've done Palermo, now it's time to explore other parts of Italy. Travel about 193 kilometers south-east to Catania to check off its top attractions. From Piazza del Duomo to Roman Amphitheatre and Duomo di Catania, you've got a jam-packed schedule ahead.
If you're eager to discover another side of Italy, consider Messina, roughly 209 kilometers east of Palermo. Duomo di Messina, Cathedral of Messina (Duomo) and Bell Tower and Astronomical Clock (Orologio Astronomico) are among its highlights.