Cheap Flights from St Louis MO to Portland ME from $279

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Flight deals from St Louis to Portland

Looking for a cheap last-minute deal or the best round-trip flight from St Louis Airport to Portland Airport? If you want to travel next month, round-trip fares start from $279. Find the lowest prices on one-way and round-trip tickets right here.

Portland.$279 per passenger.Departing Sat, Oct 31, returning Tue, Nov 3.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from St Louis on Sat, Oct 31, arriving in Portland.Inbound indirect flight with Delta, departing from Portland on Tue, Nov 3, arriving in St Louis.Price includes taxes and charges.From $279, select.

Portland.$279 per passenger.Departing Sat, Oct 17, returning Wed, Oct 21.Round-trip flight with United.Outbound indirect flight with United, departing from St Louis on Sat, Oct 17, arriving in Portland.Inbound indirect flight with United, departing from Portland on Wed, Oct 21, arriving in St Louis.Price includes taxes and charges.From $279, select.

Portland.$319 per passenger.Departing Thu, Nov 5, returning Mon, Nov 9.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from St Louis on Thu, Nov 5, arriving in Portland.Inbound indirect flight with Delta, departing from Portland on Mon, Nov 9, arriving in St Louis.Price includes taxes and charges.From $319, select.

Portland.$349 per passenger.Departing Tue, Dec 8, returning Fri, Dec 11.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from St Louis on Tue, Dec 8, arriving in Portland.Inbound indirect flight with Delta, departing from Portland on Fri, Dec 11, arriving in St Louis.Price includes taxes and charges.From $349, select.

Portland.$413 per passenger.Departing Wed, Sep 30, returning Tue, Oct 6.Round-trip flight with Frontier Airlines and jetBlue.Outbound indirect flight with Frontier Airlines, departing from St Louis on Wed, Sep 30, arriving in Portland.Inbound indirect flight with jetBlue, departing from Portland on Tue, Oct 6, arriving in St Louis.Price includes taxes and charges.From $413, select.

Portland.$432 per passenger.Departing Mon, Mar 29, returning Sat, Apr 3.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from St Louis on Mon, Mar 29, arriving in Portland.Inbound indirect flight with Delta, departing from Portland on Sat, Apr 3, arriving in St Louis.Price includes taxes and charges.From $432, select.

Portland.$454 per passenger.Departing Mon, Jul 19, returning Fri, Jul 23.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from St Louis on Mon, Jul 19, arriving in Portland.Inbound indirect flight with Delta, departing from Portland on Fri, Jul 23, arriving in St Louis.Price includes taxes and charges.From $454, select.

Portland.$966 per passenger.Departing Fri, Sep 18, returning Sun, Sep 20.Round-trip flight with Frontier Airlines and jetBlue.Outbound indirect flight with Frontier Airlines, departing from St Louis on Fri, Sep 18, arriving in Portland.Inbound indirect flight with jetBlue, departing from Portland on Sun, Sep 20, arriving in St Louis.Price includes taxes and charges.From $966, select.

Find the cheapest month to fly from St Louis to Portland

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like St Louis to Portland flights are currently cheapest in October.

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St Louis to Portland: Alternative routes

Compare routes from St Louis to Portland below. You may find an airport to fly into that's cheaper, faster, or easier than Portland.

St Louis to Portland: Flight information

The things to know before you go.

Cheapest flight found	$279
Cheapest month to fly	October

Finding cheap flights from St Louis to Portland: Frequently asked questions

How much are round-trip flights from St Louis to Portland?

The best price we found for a round-trip flight from St Louis to Portland is $279. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from St Louis to Portland?

Currently, there are no airlines that fly direct from St Louis to Portland. But we found flights with one or more stops from $279.

How many flights are there a week from St Louis to Portland?

There are no flights flying from St Louis to Portland, as of September 2026.

When is the cheapest time to fly from St Louis to Portland?

The cheapest month to fly from St Louis to Portland is usually October.

Which upcoming date is cheapest to fly from St Louis Airport to Portland Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from St Louis Airport to Portland Airport on Saturday, October 17, 2026.

Can I get a direct flight from St Louis Airport to Portland Airport?

No airlines currently offer direct flights between St Louis Airport and Portland Airport. Most routes have one or more stops.

How can I find the best flight deal to Portland?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Portland but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Portland?

We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Portland is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly with from St Louis Airport to Portland?

Currently, United offers the cheapest flight tickets to Portland.

Flying from St Louis Airport (STL) to Portland Airport (PWM): what you need to know

Arrive at the airport on time so you don't miss your STL to PWM flight. Be there at least two hours ahead for international flights and an hour early for domestic departures to avoid any last-minute rush.
You'll likely experience bigger queues in popular months such as July. Arriving up to four hours ahead of international flights and two hours for a domestic departure will help ensure a smooth travel experience.
We make it a cinch to book a flight with a stopover. To see all your options for tickets from St Louis Airport to Portland Airport, uncheck 'Direct flights only.' Then, choose a flight that has a stop long enough to visit your chosen city. Some great stopovers between STL and PWM include:
- Detroit Wayne County Airport
- Washington Ronald Reagan Airport
- Baltimore Washington International Airport

Handy information about St Louis Airport (STL)

You'll find STL at 10701 Lambert International Blvd..
Of the departures from St Louis Airport, 76% land on time at their destination.
To reach St Louis Airport from central St Louis, it'll take about 25 minutes if you're traveling by car. This depends on traffic, however. It's approximately 24 kilometers from the airport to the city center.
The trip on public transport usually takes 30 minutes.
Get your break off to a leisurely start by staying near STL. Whether you're taking an early flight from St Louis Airport to Portland Airport or just don't like being rushed, these hotels are ideal:

Arriving at Portland Airport (PWM)

Consider staying in a hotel near PWM if you're on a late St Louis Airport to Portland Airport flight. Settle into one of these accommodation options and make your arrival easier:
Grab a Portland Airport rental car and discover Portland and beyond with your own set of wheels. Dollar, Budget and Hertz are well-known companies to choose from here.
For the lowest price, book your vehicle from Portland Airport about one week before you travel.

When to fly to Portland Airport (PWM)

Before locking in your flights from St Louis Airport to Portland Airport, think about which time of year is best for you. High season in Portland offers a bustling atmosphere and lots to do, while low season means you'll get cheaper hotel rates and smaller crowds.
Before locking in your flight from St Louis Airport to Portland Airport, consider the kind of weather you like. July is the warmest month in Portland, with temperatures ranging from 14ºC (57ºF) to 25ºC (77ºF).
For cooler conditions, search for a cheap ticket from STL to PWM in January. Average temperatures are between -10ºC (14ºF) and 3ºC (37ºF) then.

Explore more of the United States

Portland is easy to fall in love with, but there are so many other corners of the United States you'll want to see. About 451 kilometers south-west of Portland, a trip to New York will keep you on the move. Start with popular sights like Central Park, Statue of Liberty and Metropolitan Museum of Art.
Boston is another favorite destination in the United States and is around 161 kilometers south-west of Portland. No journey is complete without experiencing Museum of Fine Arts Boston, Freedom Trail and USS Constitution Museum.