Cheap Flights from Myrtle Beach International Airport to Missouri from $281 Roundtrip

Flight deals from Myrtle Beach International Airport to Missouri

Looking for a cheap last-minute deal or the best roundtrip flight from Myrtle Beach International Airport to Missouri? If you want to travel next month, roundtrip fares start from $356. Find the lowest prices on one-way and roundtrip tickets right here.

St Louis.$281 per passenger.Departing Wed, Aug 26, returning Mon, Aug 31.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Myrtle Beach International on Wed, Aug 26, arriving in St Louis.Inbound indirect flight with Delta, departing from St Louis on Mon, Aug 31, arriving in Myrtle Beach International.Price includes taxes and charges.From $281, select.

Columbia.$361 per passenger.Departing Sun, Jun 28, returning Sat, Jul 4.Round-trip flight with Allegiant Air.Outbound indirect flight with Allegiant Air, departing from Myrtle Beach International on Sun, Jun 28, arriving in Columbia.Inbound indirect flight with Allegiant Air, departing from Columbia on Sat, Jul 4, arriving in Myrtle Beach International.Price includes taxes and charges.From $361, select.

Kansas City.$364 per passenger.Departing Sun, Jun 21, returning Sat, Jun 27.Round-trip flight with Allegiant Air and Frontier Airlines.Outbound indirect flight with Allegiant Air, departing from Myrtle Beach International on Sun, Jun 21, arriving in Kansas City International.Inbound indirect flight with Frontier Airlines, departing from Kansas City International on Sat, Jun 27, arriving in Myrtle Beach International.Price includes taxes and charges.From $364, select.

Springfield.$391 per passenger.Departing Fri, Jul 17, returning Sun, Jul 19.Round-trip flight with Breeze Airways and Allegiant Air.Outbound indirect flight with Breeze Airways, departing from Myrtle Beach International on Fri, Jul 17, arriving in Springfield-Branson Rg.Inbound indirect flight with Allegiant Air, departing from Springfield-Branson Rg on Sun, Jul 19, arriving in Myrtle Beach International.Price includes taxes and charges.From $391, select.

Kirksville.$952 per passenger.Departing Tue, Jun 2, returning Thu, Jun 4.Round-trip flight with Breeze Airways and Contour Airlines.Outbound indirect flight with Breeze Airways, departing from Myrtle Beach International on Tue, Jun 2, arriving in Kirksville.Inbound indirect flight with Contour Airlines, departing from Kirksville on Thu, Jun 4, arriving in Myrtle Beach International.Price includes taxes and charges.From $952, select.

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Flying from Myrtle Beach International Airport to Missouri

Arm yourself with these facts on the fly.

Cheapest flight found	$281
Cheapest month to fly	August
Average flight time	2 hrs, 20 mins
Average flights per week	5
Most popular airline	Southwest Airlines

How to find cheap flights from Myrtle Beach International Airport to Missouri

We've compared the best online travel agents and flight providers on the internet to find the cheapest plane tickets from Myrtle Beach International Airport to Missouri. Other savvy travelers recently found round-trip flights from $281 and one-way tickets from $120. Ready to join them? Here are a few tips to help you do it the smart way.

Fly in August

The cheapest time to fly from Myrtle Beach International Airport to Missouri is currently August.

Flex your dates for the best rates

If you’re flexible on your departure dates, you can use Skyscanner's whole month tool to find the cheapest day of the year to fly from Myrtle Beach International Airport to anywhere you choose in Missouri.

Watch as flight prices go up and down

With Price Alerts, we'll let you know when flight prices from Myrtle Beach International Airport to your chosen airport in Missouri go up or down so you can book when the time is just right.

Relax – these are fee-free plane tickets

With us, there are no added fees – the Missouri Airport to Missouri flight price you see when you search with us is what you pay to the provider.

Frequently asked questions

Are there any direct flights from Myrtle Beach International Airport to Missouri?

Yes – direct flights currently operate from Myrtle Beach International Airport to St Louis Airport in Missouri.

What is the average price of a flight from Myrtle Beach International Airport to Missouri?

We looked at all of the upcoming round-trip flights from Myrtle Beach International Airport to Missouri we could find over the next 12 months. It looks like $281 is the best price. This is good, compared to the average Missouri ticket price of $470.

What is the cheapest month to fly from Myrtle Beach International Airport to Missouri?

The cheapest month to fly from Myrtle Beach International Airport to Columbia Airport is currently June.
The cheapest month to fly from Myrtle Beach International Airport to Kansas City International Airport is currently June.
The cheapest month to fly from Myrtle Beach International Airport to St Louis Airport is currently August.
And the cheapest month to fly from Myrtle Beach International Airport to Springfield-Branson Rg Airport is usually July.

On which upcoming date is it cheapest to fly from Myrtle Beach International Airport to Missouri?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Myrtle Beach International Airport to Missouri on Wednesday, August 26, 2026.

If I'm flying from Myrtle Beach International Airport, where in Missouri is cheapest to fly to?

If you're flying from Myrtle Beach International, the cheapest city in Missouri to fly into is St Louis. The cheapest airport serving St Louis at the moment is St Louis.