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Cheap flights from Chicago to Irvine

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      Travelers and cabin class, 1 Adult, Economy

      Compare Chicago to Irvine flight deals

      Find the cheapest month or even day of the year to fly to Irvine

      Book the best Irvine fare with no extra fees

      Flight deals from Chicago to Irvine

      Looking for a cheap last-minute deal or the best round-trip flight from Chicago to Irvine? Find the lowest prices on one-way and round-trip tickets right here.
      Santa Ana.$186 per passenger.Departing Thu, Nov 12, returning Sun, Nov 15.Round-trip flight with Frontier Airlines and Allegiant Air.Outbound indirect flight with Frontier Airlines, departing from Chicago O'Hare International on Thu, Nov 12, arriving in Santa Ana John Wayne.Inbound indirect flight with Allegiant Air, departing from Santa Ana John Wayne on Sun, Nov 15, arriving in Chicago O'Hare International.Price includes taxes and charges.From $186, select.
      Santa Ana.$199 per passenger.Departing Wed, Sep 9, returning Wed, Sep 16.Round-trip flight with Frontier Airlines and Breeze Airways.Outbound indirect flight with Frontier Airlines, departing from Chicago O'Hare International on Wed, Sep 9, arriving in Santa Ana John Wayne.Inbound indirect flight with Breeze Airways, departing from Santa Ana John Wayne on Wed, Sep 16, arriving in Chicago O'Hare International.Price includes taxes and charges.From $199, select.
      Santa Ana.$205 per passenger.Departing Thu, Oct 22, returning Mon, Oct 26.Round-trip flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departing from Chicago O'Hare International on Thu, Oct 22, arriving in Santa Ana John Wayne.Inbound indirect flight with Frontier Airlines, departing from Santa Ana John Wayne on Mon, Oct 26, arriving in Chicago O'Hare International.Price includes taxes and charges.From $205, select.
      Santa Ana.$211 per passenger.Departing Mon, Sep 28, returning Thu, Oct 29.Round-trip flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departing from Chicago O'Hare International on Mon, Sep 28, arriving in Santa Ana John Wayne.Inbound indirect flight with Frontier Airlines, departing from Santa Ana John Wayne on Thu, Oct 29, arriving in Chicago O'Hare International.Price includes taxes and charges.From $211, select.
      Santa Ana.$211 per passenger.Departing Fri, Oct 30, returning Sun, Nov 8.Round-trip flight with Frontier Airlines and Allegiant Air.Outbound indirect flight with Frontier Airlines, departing from Chicago O'Hare International on Fri, Oct 30, arriving in Santa Ana John Wayne.Inbound indirect flight with Allegiant Air, departing from Santa Ana John Wayne on Sun, Nov 8, arriving in Chicago O'Hare International.Price includes taxes and charges.From $211, select.
      Santa Ana.$241 per passenger.Departing Wed, Nov 18, returning Wed, Dec 2.Round-trip flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departing from Chicago Midway on Wed, Nov 18, arriving in Santa Ana John Wayne.Inbound indirect flight with Southwest Airlines, departing from Santa Ana John Wayne on Wed, Dec 2, arriving in Chicago Midway.Price includes taxes and charges.From $241, select.
      Santa Ana.$265 per passenger.Departing Wed, Aug 26, returning Thu, Sep 24.Round-trip flight with Allegiant Air and Frontier Airlines.Outbound indirect flight with Allegiant Air, departing from Chicago Rockford on Wed, Aug 26, arriving in Santa Ana John Wayne.Inbound indirect flight with Frontier Airlines, departing from Santa Ana John Wayne on Thu, Sep 24, arriving in Chicago O'Hare International.Price includes taxes and charges.From $265, select.
      Santa Ana.$277 per passenger.Departing Sat, Jan 30, returning Sat, Feb 6.Round-trip flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departing from Chicago Midway on Sat, Jan 30, arriving in Santa Ana John Wayne.Inbound indirect flight with Southwest Airlines, departing from Santa Ana John Wayne on Sat, Feb 6, arriving in Chicago Midway.Price includes taxes and charges.From $277, select.
      Santa Ana.$289 per passenger.Departing Tue, Jan 5, returning Tue, Jan 12.Round-trip flight with United.Outbound direct flight with United departing from Chicago O'Hare International on Tue, Jan 5, arriving in Santa Ana John Wayne.Inbound direct flight with United departing from Santa Ana John Wayne on Tue, Jan 12, arriving in Chicago O'Hare International.Price includes taxes and charges.From $289, select.
      Santa Ana.$289 per passenger.Departing Tue, Dec 8, returning Sat, Dec 12.Round-trip flight with Alaska Airlines.Outbound indirect flight with Alaska Airlines, departing from Chicago O'Hare International on Tue, Dec 8, arriving in Santa Ana John Wayne.Inbound indirect flight with Alaska Airlines, departing from Santa Ana John Wayne on Sat, Dec 12, arriving in Chicago O'Hare International.Price includes taxes and charges.From $289, select.
      Santa Ana.$289 per passenger.Departing Sat, Sep 19, returning Sat, Oct 3.Round-trip flight with United.Outbound direct flight with United departing from Chicago O'Hare International on Sat, Sep 19, arriving in Santa Ana John Wayne.Inbound direct flight with United departing from Santa Ana John Wayne on Sat, Oct 3, arriving in Chicago O'Hare International.Price includes taxes and charges.From $289, select.
      Santa Ana.$289 per passenger.Departing Sat, Sep 5, returning Sat, Sep 12.Round-trip flight with American Airlines.Outbound direct flight with American Airlines departing from Chicago O'Hare International on Sat, Sep 5, arriving in Santa Ana John Wayne.Inbound direct flight with American Airlines departing from Santa Ana John Wayne on Sat, Sep 12, arriving in Chicago O'Hare International.Price includes taxes and charges.From $289, select.
      Santa Ana.$289 per passenger.Departing Tue, Oct 20, returning Tue, Oct 27.Round-trip flight with United.Outbound direct flight with United departing from Chicago O'Hare International on Tue, Oct 20, arriving in Santa Ana John Wayne.Inbound direct flight with United departing from Santa Ana John Wayne on Tue, Oct 27, arriving in Chicago O'Hare International.Price includes taxes and charges.From $289, select.
      Santa Ana.$299 per passenger.Departing Wed, Aug 26, returning Sun, Aug 30.Round-trip flight with Allegiant Air and Frontier Airlines.Outbound indirect flight with Allegiant Air, departing from Chicago Rockford on Wed, Aug 26, arriving in Santa Ana John Wayne.Inbound indirect flight with Frontier Airlines, departing from Santa Ana John Wayne on Sun, Aug 30, arriving in Chicago Rockford.Price includes taxes and charges.From $299, select.
      Santa Ana.$300 per passenger.Departing Tue, Mar 2, returning Sat, Mar 6.Round-trip flight with Alaska Airlines.Outbound indirect flight with Alaska Airlines, departing from Chicago O'Hare International on Tue, Mar 2, arriving in Santa Ana John Wayne.Inbound indirect flight with Alaska Airlines, departing from Santa Ana John Wayne on Sat, Mar 6, arriving in Chicago O'Hare International.Price includes taxes and charges.From $300, select.
      Santa Ana.$300 per passenger.Departing Fri, Feb 5, returning Mon, Feb 8.Round-trip flight with Alaska Airlines.Outbound indirect flight with Alaska Airlines, departing from Chicago O'Hare International on Fri, Feb 5, arriving in Santa Ana John Wayne.Inbound indirect flight with Alaska Airlines, departing from Santa Ana John Wayne on Mon, Feb 8, arriving in Chicago O'Hare International.Price includes taxes and charges.From $300, select.
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      Chicago to Irvine: Flight information

      The things to know before you go.
      Fly intoSanta Ana John Wayne Airport
      Distance to Irvine6.8 km
      Cheapest flight$186
      Cheapest month to flyNovember
      Most popular airlineUnited
      Average flight time4 hrs, 34 mins

      Find the cheapest month to fly from Chicago to Irvine

      We always keep an eye on fares, so you can find the best flight deal in seconds. It looks like Chicago to Irvine flights are currently cheapest in November. We’ve based this on flights into Santa Ana John Wayne Airport.
      Aug
      from $299
      Sep
      from $199
      Oct
      from $205
      Nov
      from $186
      Dec
      from $289
      Jan
      from $289
      Feb
      from $300
      Mar
      from $300
      Apr
      from $301
      May
      from $301
      Jun
      from $300
      Jul
      from $493

      Finding cheap flights from Chicago to Irvine: Frequently asked questions

      There are three (3) airports near Irvine: Santa Ana John Wayne Airport, Long Beach Municipal Airport, and Ontario International Airport.
      The best price we found for a round-trip flight from Chicago to Irvine is $186. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      United, American Airlines, and Alaska Airlines all offer direct flights to Santa Ana John Wayne Airport.
      We've checked every Chicago to Irvine fare we could find, and the cheapest upcoming date to fly seems to be on Thursday, November 12, 2026. Overall, the cheapest month to fly from Chicago to Irvine is usually November.
      If you're flying from Chicago, the cheapest airport near Irvine is Santa Ana John Wayne – which is 6.8 km away from the center of Irvine. We've found flights to this airport from $186.
      After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Chicago to Irvine on Thursday, November 12, 2026.
      No airlines currently offer direct flights between Chicago and Irvine. Most routes have one or more stops.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Irvine but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Irvine is around 40 days in advance, so don’t leave your flight to the last minute.

      Santa Ana John Wayne Airport is 6.8km from Irvine, Long Beach Municipal Airport is 36.2km from Irvine, and Ontario International Airport is 44.9km from Irvine.
      Santa Ana John Wayne Airport is closest to Irvine, at around 6.8 km away.
      The cheapest airline that flies to Irvine is Frontier Airlines, and the cheapest airline that flies to Long Beach Municipal Airport is American Airlines.