Cheap flights from Port Columbus to Greenville-Spartanburg

Compare Port Columbus to Greenville-Spartanburg flight deals

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Flight deals from Port Columbus to Greenville-Spartanburg

Looking for a cheap last-minute deal or the best round-trip flight from Port Columbus to Greenville-Spartanburg? Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Port Columbus to Greenville-Spartanburg

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Port Columbus to Greenville-Spartanburg flights are currently cheapest in September.

Direct flights from Port Columbus to Greenville-Spartanburg

Port Columbus to Greenville-Spartanburg: Alternative routes

Compare routes from Port Columbus to Greenville below. You may find an airport to fly into that's cheaper, faster, or easier than Greenville-Spartanburg.

Columbus to Greenville: Flight information

The things to know before you go.
Cheapest flight found$98
Cheapest month to flySeptember
Average flight time1 hr, 20 mins
Most popular airlineBreeze Airways
Average flights per week2

Finding cheap flights from Port Columbus to Greenville-Spartanburg: Frequently asked questions

The best price we found for a round-trip flight from Port Columbus to Greenville-Spartanburg is $98. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 20 minutes is the average flight time from Port Columbus to Greenville-Spartanburg.
Breeze Airways flies direct from Port Columbus to Greenville-Spartanburg.
There are 2 flights per week flying from Port Columbus to Greenville-Spartanburg, as of February 2026.
The cheapest month to fly from Port Columbus to Greenville-Spartanburg is usually September.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Port Columbus Airport to Greenville-Spartanburg Airport on Monday, September 7, 2026.
Yes – the average flight time is 1 hour and 20 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Greenville-Spartanburg but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Greenville is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Breeze Airways offers the cheapest flight tickets to Greenville-Spartanburg.

Traveling from John Glenn Columbus International Airport (CMH) to Greenville-Spartanburg International Airport (GSP): what you need to know

  • Your CMH to GSP flight won't wait if you're running late, so get to the airport on time. Arrive up to one hour in advance for domestic flights and two hours ahead for international travel.

  • During popular months like July, it's a good idea to get to the airport earlier than usual. Plan to arrive two hours before a domestic departure and four hours ahead of an international flight whenever you're traveling during a peak period in general.

  • Consider adding a stopover when booking your ticket from John Glenn Columbus International Airport to Greenville-Spartanburg International Airport. Just deselect 'Direct flights only' to break up your journey, or enjoy a detour to a new and interesting place. Here's where you can stop between CMH and GSP:

    • Hartsfield-Jackson Atlanta International Airport

    • Charlotte Douglas International Airport

    • Baltimore/Wash International Thurgood Marshall Airport

How to find the cheapest flights from John Glenn Columbus International Airport (CMH) to Greenville-Spartanburg International Airport (GSP)

  • Right now, $49 is the lowest price we've found for a one-way John Glenn Columbus International Airport to Greenville-Spartanburg International Airport flight. The best price for a return plane ticket is $98. Remember that fares could change due to availability at the time of booking.

  • Don't wait until the last moment. You're more likely to get cheap tickets from CMH to GSP if you book in advance. Airlines often have some amazing early bird deals.

  • If you're willing to be flexible with your travel plans, try using the 'Whole month' search function. It'll find the lowest price across the month when looking for a flight from John Glenn Columbus International Airport to Greenville-Spartanburg International Airport.

  • Never miss a deal on cheap flights from CMH to GSP by creating a Price Alert. We'll send you an email or notification through the app when a lower fare becomes available.

  • Discover the right flight for you with the help of the filters. To see the 'Best,' 'Fastest' or 'Cheapest' flights from John Glenn Columbus International Airport to Greenville-Spartanburg International Airport, use the 'Sort by' function. You can also filter results by airline, departure and arrival times, and journey duration.

Handy information about John Glenn Columbus International Airport (CMH)

  • You'll find CMH at 4600 International Gateway.

  • 79.5% of flights that take off from John Glenn Columbus International Airport make it to their destination on schedule.

  • To get to John Glenn Columbus International Airport from central Columbus, it'll take about 10 minutes by car. This depends on traffic, however. It's approximately 13 kilometers from the airport to the city center.

  • The journey when using public transport will take about 1 hour 5 minutes.

  • Get your travels off to a stress-free start by staying near CMH. Whether you're boarding an early flight from John Glenn Columbus International Airport to Greenville-Spartanburg International Airport or just don't want to be rushed, these stays are ideal:

Arriving at Greenville-Spartanburg International Airport (GSP)

Getting from Greenville-Spartanburg International Airport (GSP) to central Greenville

  • You'll find GSP at 2000 GPS Drive, Suite 1.

  • Greenville-Spartanburg International Airport is approximately 27 kilometers from central Greenville. The drive time takes around 20 minutes.

When to fly to Greenville-Spartanburg International Airport (GSP)

  • It's time to choose your travel dates for your flight from John Glenn Columbus International Airport to Greenville-Spartanburg International Airport. August is the most popular month to visit Greenville. If you want a more laid-back vibe, go in February.

  • Book your flight from John Glenn Columbus International Airport to Greenville-Spartanburg International Airport for July if you want to explore Greenville during its warmest month. Expect temperatures of between 19ºC (66ºF) and 34ºC (93ºF).

  • Look for cheap tickets from CMH to GSP in January if you want to travel in cooler conditions. Temperatures are at their lowest then, ranging between -3ºC (27ºF) and 13ºC (55ºF) on average.

Explore more of United States

  • Charlotte is just one of the many places in United States waiting to be discovered after you've seen Greenville. Around 145 kilometers away to the east, its best attractions include NASCAR Hall of Fame, Freedom Park and Carolinas Aviation Museum.

  • Around 418 kilometers west of Greenville, Nashville is another essential stop in United States. Experience this destination's highlights firsthand at Grand Ole Opry, Country Music Hall of Fame and Museum and Ryman Auditorium.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.