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Cheap flights from Des Moines to Phoenix

Compare Des Moines to Phoenix flight deals

Find the cheapest month or even day of the year to fly to Phoenix

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Flight deals from Des Moines to Phoenix

Looking for a cheap last-minute deal or the best round-trip flight from Des Moines to Phoenix? Find the lowest prices on one-way and round-trip tickets right here.
Phoenix.$110 per passenger.Departing Fri, Oct 3, returning Fri, Oct 10.Round-trip flight with Allegiant Air.Outbound direct flight with Allegiant Air departing from Des Moines on Fri, Oct 3, arriving in Phoenix-Mesa Gateway.Inbound direct flight with Allegiant Air departing from Phoenix-Mesa Gateway on Fri, Oct 10, arriving in Des Moines.Price includes taxes and charges.From $110, select.
Phoenix.$136 per passenger.Departing Mon, Dec 1, returning Fri, Dec 5.Round-trip flight with Allegiant Air.Outbound direct flight with Allegiant Air departing from Des Moines on Mon, Dec 1, arriving in Phoenix-Mesa Gateway.Inbound direct flight with Allegiant Air departing from Phoenix-Mesa Gateway on Fri, Dec 5, arriving in Des Moines.Price includes taxes and charges.From $136, select.
Phoenix.$143 per passenger.Departing Fri, Nov 7, returning Sun, Nov 9.Round-trip flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departing from Des Moines on Fri, Nov 7, arriving in Phoenix Sky Harbor.Inbound indirect flight with Frontier Airlines, departing from Phoenix Sky Harbor on Sun, Nov 9, arriving in Des Moines.Price includes taxes and charges.From $143, select.
Phoenix.$143 per passenger.Departing Thu, Sep 25, returning Sun, Sep 28.Round-trip flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departing from Des Moines on Thu, Sep 25, arriving in Phoenix Sky Harbor.Inbound indirect flight with Frontier Airlines, departing from Phoenix Sky Harbor on Sun, Sep 28, arriving in Des Moines.Price includes taxes and charges.From $143, select.
Phoenix.$145 per passenger.Departing Fri, Sep 19, returning Fri, Oct 10.Round-trip flight with Allegiant Air.Outbound direct flight with Allegiant Air departing from Des Moines on Fri, Sep 19, arriving in Phoenix-Mesa Gateway.Inbound direct flight with Allegiant Air departing from Phoenix-Mesa Gateway on Fri, Oct 10, arriving in Des Moines.Price includes taxes and charges.From $145, select.
Phoenix.$155 per passenger.Departing Sat, Nov 29, returning Fri, Dec 5.Round-trip flight with Allegiant Air.Outbound direct flight with Allegiant Air departing from Des Moines on Sat, Nov 29, arriving in Phoenix-Mesa Gateway.Inbound direct flight with Allegiant Air departing from Phoenix-Mesa Gateway on Fri, Dec 5, arriving in Des Moines.Price includes taxes and charges.From $155, select.
Phoenix.$158 per passenger.Departing Fri, Sep 5, returning Fri, Sep 12.Round-trip flight with Allegiant Air.Outbound direct flight with Allegiant Air departing from Des Moines on Fri, Sep 5, arriving in Phoenix-Mesa Gateway.Inbound direct flight with Allegiant Air departing from Phoenix-Mesa Gateway on Fri, Sep 12, arriving in Des Moines.Price includes taxes and charges.From $158, select.
Phoenix.$186 per passenger.Departing Fri, Jan 9, returning Sat, Jan 17.Round-trip flight with Allegiant Air.Outbound direct flight with Allegiant Air departing from Des Moines on Fri, Jan 9, arriving in Phoenix-Mesa Gateway.Inbound direct flight with Allegiant Air departing from Phoenix-Mesa Gateway on Sat, Jan 17, arriving in Des Moines.Price includes taxes and charges.From $186, select.

Find the cheapest month to fly from Des Moines to Phoenix

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Des Moines to Phoenix flights are currently cheapest in October.
Aug
from $209
Sep
from $143
Oct
from $110
Nov
from $143
Dec
from $136
Jan
from $186
Feb
from $299
Mar
from $307
Apr
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May
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Jun
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Jul
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Direct flights from Des Moines to Phoenix

Alternative Des Moines to Phoenix routes

Looking for the cheapest, fastest or easiest route from Des Moines to Phoenix? You could fly into the following airports instead.

Des Moines to Phoenix: Flight information

The things to know before you go.
Cheapest flight found$110
Cheapest month to flyOctober
Average flight time3 hrs, 12 mins
Most popular airlineAmerican Airlines
Average flights per week64

Finding cheap flights from Des Moines to Phoenix: Frequently asked questions

There are 4 airports in Phoenix: Phoenix Sky Harbor, Phoenix Scottsdale Municipal, Phoenix-Deer Valley, and Phoenix-Mesa Gateway.
The best price we found for a round-trip flight from Des Moines to Phoenix is $110. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
3 hours and 11 minutes is the average flight time from Des Moines to Phoenix.
American Airlines, Alaska Airlines and SkyWest Airlines fly direct from Des Moines to Phoenix.
There are 64 flights per week flying from Des Moines to Phoenix, as of August 2025.
The cheapest month to fly from Des Moines to Phoenix is usually October.
If you're flying from Des Moines Airport, the cheapest airport near Phoenix is Phoenix-Mesa Gateway – which is 41.9 km away from the center of Phoenix. We've found flights to this airport from $110.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Des Moines Airport to Phoenix on Friday, October 3, 2025.
Yes – the average flight time is 3 hours and 11 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Phoenix but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Phoenix is around 40 days in advance, so don’t leave your flight to the last minute.
In August, the average temperature is usually around 32°C. July is typically the warmest month in Phoenix, when it usually averages around 40°C. You can expect the least rain in June. The coldest month is December, with temperatures averaging 4°C. The rainiest month is August.
Currently, Allegiant Air offers the cheapest flight tickets to Phoenix.

Flying from Des Moines International Airport (DSM) to Phoenix: what you need to know

  • The average length of a direct flight from Des Moines International Airport to Phoenix is 2 hours 50 minutes.

  • Phoenix is two hours behind Des Moines, where Des Moines International Airport is located. Phoenix follows the UTC-7 timezone.

  • With 19 weekly flights between the two airports, Des Moines International Airport (DSM) to Phoenix Sky Harbor International Airport (PHX) is the most popular route. American Airlines operates the earliest flight at 05:00. If you're eager to get more out of your day before taking off, the latest departure from DSM to PHX is with American Airlines at 18:53.

  • Leave enough time to get on your DSM to Phoenix flight. A good rule of thumb is to arrive two hours before international departures and an hour ahead for domestic flights.

  • If you're jetting off during a major holiday or another peak period, give yourself extra time. A good rule is two hours ahead of domestic flights and up to four hours before international departures. Check-in and security lines will be longer.

  • Begin your journey at DSM and travel nonstop to Phoenix Sky Harbor International Airport (PHX). That's where you can expect to land when searching for Des Moines International Airport to Phoenix tickets.

  • You'll have your pick of carriers that operate direct flights from Des Moines International Airport to Phoenix. Get on board with any of these:

  • DSM is about 6 kilometers from central Des Moines. If you're catching a cab, driving or ride-sharing from the center, it'll take 15 minutes or so to get there, depending on traffic. If you're planning to take public transport, expect the travel time to be around 45 minutes.

  • Have an early flight from Des Moines International Airport to Phoenix? Avoid the last-minute rush to the airport (and sneak in some extra precious sleep) by choosing one of these stays near DSM:

  • Des Moines International Airport maintains a solid on-time performance, making delays less likely. Departures from DSM touch down on schedule 80.45% of the time.

  • DSM is located at 5800 Fleur Drive, Suite 201.

How to find the cheapest flights from Des Moines International Airport (DSM) to Phoenix

  • $59 is the lowest price we've found for a one-way Des Moines International Airport to Phoenix flight. A round-trip flight ticket right now is $110. Depending on the availability when you book, these fares may change.

  • Book one month before you want to travel. Pricing trends show that this is the ideal window for finding cheap flights from DSM to Phoenix.

  • The best month for landing cheap Des Moines International Airport to Phoenix tickets is May. Use the 'Whole month' tool to compare flight prices, then select the dates that offer the lowest fares.

  • Locking in a cheap flight from DSM to Phoenix couldn't be easier with Price Alerts. Simply create one of these automatic notifications and we'll notify you when there's a better deal.

  • Tailor your trip with filters. Choose your ideal arrival and departure times, airlines and total journey duration. You can also sort your results by 'Fastest,' 'Best' or 'Cheapest' flights from Des Moines International Airport to Phoenix.

Airports in Phoenix

Phoenix Scottsdale Municipal Airport (SCF)

  • Phoenix Scottsdale Municipal Airport (SCF) to central Phoenix takes about 35 minutes by car. The center is roughly 32 kilometers away.

  • Getting to the center on public transport will take you around 1 hour 55 minutes.

  • If you're coming in on a late flight from Des Moines International Airport to Phoenix, nothing beats the convenience of staying close to the terminal. Grab your luggage from the carousel and then be showered and snoozing not long after at one of these accommodation options near SCF:

Phoenix Sky Harbor International Airport (PHX)

  • The center of Phoenix is about 8 kilometers from Phoenix Sky Harbor International Airport (PHX). Once your flight from Des Moines International Airport to Phoenix has landed and you've made your way to arrivals, the drive should take about 10 minutes.

  • If you choose to travel on public transport, you'll get to the city center in 35 minutes or so.

  • There are some great places to rest your head close to PHX. Kick back and get cozy after your DSM to Phoenix flight at any of these perfectly located options:

  • Europcar, Dollar and Thrifty make collecting a Phoenix Sky Harbor International Airport rental car quick and easy. These providers are located in or around the terminal and will have you ready to go in a flash.

  • Avoid potential price surges. Booking your ride one week ahead of your arrival at PHX can get you a lower rate.

  • The address for Phoenix Sky Harbor International Airport is 3400 Sky Harbor Boulevard.

Phoenix-Mesa Gateway Airport (AZA)

  • Phoenix-Mesa Gateway Airport (AZA) is around 56 kilometers from the center of Phoenix. It takes about 40 minutes to get to the city center in a cab or ride-share once you've hopped off your flight from Des Moines International Airport to Phoenix.

  • If you don't want to make the journey to the center, find a hotel close to AZA. Make yourself comfortable at one of these stays after your DSM to Phoenix flight:

  • Begin your journey without worrying about how to get to your destination with a Phoenix-Mesa Gateway Airport rental car. Book your ideal wheels with trusted companies here like Dollar, Alamo and Budget.

  • About two weeks ahead of your flight from Des Moines International Airport to Phoenix is the ideal time to book your vehicle from AZA. You're more likely to get a better rate or score some early bird savings.

  • The street address for Phoenix-Mesa Gateway Airport is 6033 S. Sossaman Rd..

Best time to go to Phoenix

  • Carefully consider your travel dates before locking in your flight from Des Moines International Airport to Phoenix. The city buzzes during peak season, but hotel rates are usually higher and major attractions can be busy. Go to Phoenix in the off-season if you like a quieter vibe.

  • Book a Des Moines International Airport to Phoenix flight ticket with a departure in July to visit the city during its warmest month. Expect temperatures to range from 26ºC (79ºF) to 44ºC (111ºF).

  • January sees average temperatures of between 4ºC (39ºF) and 20ºC (68ºF). Look for a cheap ticket from DSM to Phoenix around that time if you like cooler conditions.

More about Phoenix

Explore more of United States

  • San Diego is just one of the many cities in United States waiting to be explored after you've seen Phoenix. Around 483 kilometers away to the west, top sights here include San Diego Zoo, USS Midway Museum and SeaWorld San Diego.

  • Las Vegas is another must-experience destination in United States and is around 418 kilometers north-west of Phoenix. No trip is complete without seeing Las Vegas Strip, Fountains of Bellagio and Fremont Street Experience.

Plan the rest of your trip from Des Moines to Phoenix

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.