Cheap flights from Frankfurt am Main to Mytilene

Compare Frankfurt am Main to Mytilene flight deals

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Flight deals from Frankfurt am Main to Mytilene

Looking for a cheap last-minute deal or the best round-trip flight from Frankfurt am Main Airport to Mytilene Airport? If you want to travel next month, round-trip fares start from $322. Find the lowest prices on one-way and round-trip tickets right here.

Mytilene.$259 per passenger.Departing Sun, Nov 15, returning Tue, Nov 17.Round-trip flight with SKY express and Aegean Airlines.Outbound indirect flight with SKY express, departing from Frankfurt am Main on Sun, Nov 15, arriving in Mytilene.Inbound indirect flight with Aegean Airlines, departing from Mytilene on Tue, Nov 17, arriving in Frankfurt am Main.Price includes taxes and charges.From $259, select.

Mytilene.$275 per passenger.Departing Mon, Mar 1, returning Wed, Mar 10.Round-trip flight with SKY express.Outbound indirect flight with SKY express, departing from Frankfurt am Main on Mon, Mar 1, arriving in Mytilene.Inbound indirect flight with SKY express, departing from Mytilene on Wed, Mar 10, arriving in Frankfurt am Main.Price includes taxes and charges.From $275, select.

Mytilene.$302 per passenger.Departing Sat, Oct 31, returning Tue, Nov 17.Round-trip flight with SKY express.Outbound indirect flight with SKY express, departing from Frankfurt am Main on Sat, Oct 31, arriving in Mytilene.Inbound indirect flight with SKY express, departing from Mytilene on Tue, Nov 17, arriving in Frankfurt am Main.Price includes taxes and charges.From $302, select.

Mytilene.$316 per passenger.Departing Tue, May 19, returning Thu, May 28.Round-trip flight with Aegean Airlines.Outbound indirect flight with Aegean Airlines, departing from Frankfurt am Main on Tue, May 19, arriving in Mytilene.Inbound indirect flight with Aegean Airlines, departing from Mytilene on Thu, May 28, arriving in Frankfurt am Main.Price includes taxes and charges.From $316, select.

Mytilene.$322 per passenger.Departing Fri, Jun 12, returning Fri, Jun 19.Round-trip flight with Brussels Airlines.Outbound indirect flight with Brussels Airlines, departing from Frankfurt am Main on Fri, Jun 12, arriving in Mytilene.Inbound indirect flight with Brussels Airlines, departing from Mytilene on Fri, Jun 19, arriving in Frankfurt am Main.Price includes taxes and charges.From $322, select.

Mytilene.$343 per passenger.Departing Wed, Sep 23, returning Wed, Sep 30.Round-trip flight with SKY express and Aegean Airlines.Outbound indirect flight with SKY express, departing from Frankfurt am Main on Wed, Sep 23, arriving in Mytilene.Inbound indirect flight with Aegean Airlines, departing from Mytilene on Wed, Sep 30, arriving in Frankfurt am Main.Price includes taxes and charges.From $343, select.

Mytilene.$367 per passenger.Departing Thu, Sep 24, returning Thu, Oct 1.Round-trip flight with SKY express.Outbound indirect flight with SKY express, departing from Frankfurt am Main on Thu, Sep 24, arriving in Mytilene.Inbound indirect flight with SKY express, departing from Mytilene on Thu, Oct 1, arriving in Frankfurt am Main.Price includes taxes and charges.From $367, select.

Mytilene.$373 per passenger.Departing Mon, Jun 15, returning Thu, Jul 2.Round-trip flight with SKY express.Outbound indirect flight with SKY express, departing from Frankfurt am Main on Mon, Jun 15, arriving in Mytilene.Inbound indirect flight with SKY express, departing from Mytilene on Thu, Jul 2, arriving in Frankfurt am Main.Price includes taxes and charges.From $373, select.

Mytilene.$378 per passenger.Departing Thu, Aug 27, returning Wed, Sep 2.Round-trip flight with SKY express.Outbound indirect flight with SKY express, departing from Frankfurt am Main on Thu, Aug 27, arriving in Mytilene.Inbound indirect flight with SKY express, departing from Mytilene on Wed, Sep 2, arriving in Frankfurt am Main.Price includes taxes and charges.From $378, select.

Mytilene.$382 per passenger.Departing Fri, May 22, returning Fri, Jun 5.Round-trip flight with Brussels Airlines.Outbound indirect flight with Brussels Airlines, departing from Frankfurt am Main on Fri, May 22, arriving in Mytilene.Inbound indirect flight with Brussels Airlines, departing from Mytilene on Fri, Jun 5, arriving in Frankfurt am Main.Price includes taxes and charges.From $382, select.

Mytilene.$393 per passenger.Departing Thu, Oct 15, returning Mon, Oct 19.Round-trip flight with SKY express.Outbound indirect flight with SKY express, departing from Frankfurt am Main on Thu, Oct 15, arriving in Mytilene.Inbound indirect flight with SKY express, departing from Mytilene on Mon, Oct 19, arriving in Frankfurt am Main.Price includes taxes and charges.From $393, select.

Mytilene.$410 per passenger.Departing Tue, Jul 14, returning Tue, Jul 21.Round-trip flight with SKY express.Outbound indirect flight with SKY express, departing from Frankfurt am Main on Tue, Jul 14, arriving in Mytilene.Inbound indirect flight with SKY express, departing from Mytilene on Tue, Jul 21, arriving in Frankfurt am Main.Price includes taxes and charges.From $410, select.

Mytilene.$483 per passenger.Departing Wed, Aug 26, returning Thu, Aug 27.Round-trip flight with SKY express.Outbound indirect flight with SKY express, departing from Frankfurt am Main on Wed, Aug 26, arriving in Mytilene.Inbound indirect flight with SKY express, departing from Mytilene on Thu, Aug 27, arriving in Frankfurt am Main.Price includes taxes and charges.From $483, select.

Mytilene.$534 per passenger.Departing Sat, Jun 27, returning Sat, Aug 1.Round-trip flight with Aegean Airlines.Outbound indirect flight with Aegean Airlines, departing from Frankfurt am Main on Sat, Jun 27, arriving in Mytilene.Inbound indirect flight with Aegean Airlines, departing from Mytilene on Sat, Aug 1, arriving in Frankfurt am Main.Price includes taxes and charges.From $534, select.

Mytilene.$545 per passenger.Departing Fri, Jul 24, returning Wed, Aug 12.Round-trip flight with SKY express.Outbound indirect flight with SKY express, departing from Frankfurt am Main on Fri, Jul 24, arriving in Mytilene.Inbound indirect flight with SKY express, departing from Mytilene on Wed, Aug 12, arriving in Frankfurt am Main.Price includes taxes and charges.From $545, select.

Mytilene.$549 per passenger.Departing Fri, Aug 21, returning Sat, Oct 10.Round-trip flight with SKY express and Aegean Airlines.Outbound indirect flight with SKY express, departing from Frankfurt am Main on Fri, Aug 21, arriving in Mytilene.Inbound indirect flight with Aegean Airlines, departing from Mytilene on Sat, Oct 10, arriving in Frankfurt am Main.Price includes taxes and charges.From $549, select.

Find the cheapest month to fly from Frankfurt am Main to Mytilene

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Frankfurt am Main to Mytilene flights are currently cheapest in November.

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Frankfurt am Main to Mytilene: Alternative routes

Compare routes from Frankfurt am Main to Mytilene below. You may find an airport to fly into that's cheaper, faster, or easier than Mytilene.

Mytilene

7km from central Mytilene

ClosestCheapest

from $259

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Frankfurt to Mytilene: Flight information

The things to know before you go.

Cheapest flight found	$259
Cheapest month to fly	November

Finding cheap flights from Frankfurt am Main to Mytilene: Frequently asked questions

How much are round-trip flights from Frankfurt am Main to Mytilene?

The best price we found for a round-trip flight from Frankfurt am Main to Mytilene is $259. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Frankfurt am Main to Mytilene?

Currently, there are no airlines that fly direct from Frankfurt am Main to Mytilene. But we found flights with one or more stops from $259.

How many flights are there a week from Frankfurt am Main to Mytilene?

There are no flights flying from Frankfurt am Main to Mytilene, as of May 2026.

When is the cheapest time to fly from Frankfurt am Main to Mytilene?

The cheapest month to fly from Frankfurt am Main to Mytilene is usually November.

Which upcoming date is cheapest to fly from Frankfurt am Main Airport to Mytilene Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Frankfurt am Main Airport to Mytilene Airport on Sunday, November 15, 2026.

Can I get a direct flight from Frankfurt am Main Airport to Mytilene Airport?

No airlines currently offer direct flights between Frankfurt am Main Airport and Mytilene Airport. Most routes have one or more stops.

How can I find the best flight deal to Mytilene?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Mytilene but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Mytilene?

We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Mytilene is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly with from Frankfurt am Main Airport to Mytilene?

Currently, SKY express offers the cheapest flight tickets to Mytilene.

Flying from Frankfurt Airport (FRA) to Mytilene International Airport (MJT): what you need to know

Mytilene's timezone is UTC+2, which makes Mytilene one hour ahead of Frankfurt.
Arrive at the airport on time so you don't miss your FRA to MJT flight. Be there at least two hours ahead for international flights and an hour early for domestic departures to avoid the stress of rushing.
Traveling during a peak month such as April? Public holidays and other high seasons can lead to longer queues and delays at check-in and security. Play it safe and get there up to four hours ahead of international flights and two hours before a domestic departure.
If you'd like to explore another city along the way, simply uncheck 'Direct flights only' when searching for your ticket from Frankfurt Airport to Mytilene International Airport. Here are the most popular stopovers between FRA and MJT:
- Eleftherios Venizelos International Airport
- Brussels Airport
- Thessaloniki International Airport

How to find the cheapest flights from Frankfurt Airport (FRA) to Mytilene International Airport (MJT)

The lowest price we've found for a one-way Frankfurt Airport to Mytilene International Airport flight is $139. A return ticket right now is $259. Depending on the availability and when you book, these fares could change.
It's usually best to book in advance if you want to get cheap tickets from FRA to MJT. That's because flight prices are based on demand, which tends to increase closer to the date of departure.
The 'Whole month' tool shows you the cheapest flights from Frankfurt Airport to Mytilene International Airport throughout the entire month. It's a good way to find a bargain if your dates are flexible.
You won't have to check every day to find out if fares have dropped when you set up a Price Alert. We'll notify you as soon as the price changes on cheap flights from FRA to MJT.
Tailor your trip with filters. Select your ideal departure and arrival times, total journey duration and airlines. You can also sort the results by 'Fastest,' 'Best' or 'Cheapest' flights from Frankfurt Airport to Mytilene International Airport.

Handy information about Frankfurt Airport (FRA)

Of all flights leaving Frankfurt Airport, 67.47% arrive on time at their destination.
Central Frankfurt to Frankfurt Airport is around 14 kilometers. Depending on traffic, it'll take about 20 minutes to get there if you're driving, catching a cab or ride-sharing.
The trip when using public transport will take about 35 minutes.
Catching an early flight from Frankfurt Airport to Mytilene International Airport? Avoid the hassle of rushing to the airport (and enjoy a little extra shut-eye) by choosing one of these hotels near FRA:

Arriving at Mytilene International Airport (MJT)

The last thing you need is a lengthy journey to your hotel if you're getting in late on a Frankfurt Airport to Mytilene International Airport flight. Reserve one of these accommodation options near MJT instead:
Fast-track your adventure by picking up a Mytilene International Airport rental car. Grab your wheels from Exer Rent A Car, Alamo or Thrifty and explore beyond Mytilene's main sights.
To get the lowest price, reserve your vehicle from Mytilene International Airport about one week ahead.

Getting from Mytilene International Airport (MJT) to central Mytilene

From Mytilene International Airport, Mytilene is approximately 6 kilometers away. It takes around 10 minutes to drive to the center.

When to fly to Mytilene International Airport (MJT)

It's time to pick your dates for your flight from Frankfurt Airport to Mytilene International Airport. July is the busiest month to visit Mytilene. If you'd like a more low-key vibe, go in February.
Lock in your flight from Frankfurt Airport to Mytilene International Airport for August if you'd like to go to Mytilene during its warmest month. Expect temperatures of between 21ºC (70ºF) and 31ºC (88ºF).
If you'd rather travel in cooler conditions, look for a cheap ticket from FRA to MJT in January. Average temperatures are between 4ºC (39ºF) and 14ºC (57ºF) then.

Explore more of Greece

Mytilene is easy to fall in love with, but there are so many other corners of Greece just waiting to be explored. Around 274 kilometers south-west of Mytilene, a visit to Athens will keep you busy. Check out popular attractions like Museum of the Center for the Acropolis Studies, Acropolis of Athens and The Parthenon.
If you're interested in discovering another well-known destination in Greece, consider Thessaloniki, about 354 kilometers north-west of Mytilene. Arch of Galerius, Aristotelous Square and Museum of Byzantine Culture are highlights.