Cheap flights from Gainesville to St Louis

Roundtrip selected
Roundtrip selected
origin
Enter the city you're flying from, or choose from the options below
Include nearby airports
    selected
    destination
    . Enter your destination, or choose from the options below
    Include nearby airports
      selected
      Travelers and cabin class, 1 Adult, Economy

      Compare Gainesville to St Louis flight deals

      Find the cheapest month or even day of the year to fly to St Louis

      Book the best St Louis fare with no extra fees

      Flight deals from Gainesville to St Louis

      Looking for a cheap last-minute deal or the best round-trip flight from Gainesville Airport to St Louis Airport? If you want to travel next month, round-trip fares start from $427. Find the lowest prices on one-way and round-trip tickets right here.

      Find the cheapest month to fly from Gainesville to St Louis

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Gainesville to St Louis flights are currently cheapest in September.

      Gainesville to St Louis: Alternative routes

      Compare routes from Gainesville to St Louis below. You may find an airport to fly into that's cheaper, faster, or easier than St Louis.

      Gainesville to St Louis: Flight information

      The things to know before you go.
      Cheapest flight found$401
      Cheapest month to flySeptember

      Finding cheap flights from Gainesville to St Louis: Frequently asked questions

      The best price we found for a round-trip flight from Gainesville to St Louis is $401. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      Currently, there are no airlines that fly direct from Gainesville to St Louis. But we found flights with one or more stops from $401.
      There are no flights flying from Gainesville to St Louis, as of August 2026.
      The cheapest month to fly from Gainesville to St Louis is usually September.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Gainesville Airport to St Louis Airport on Wednesday, September 30, 2026.
      No airlines currently offer direct flights between Gainesville Airport and St Louis Airport. Most routes have one or more stops.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to St Louis but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

      We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to St Louis is around 40 days in advance, so don’t leave your flight to the last minute.

      Currently, Delta offers the cheapest flight tickets to St Louis.

      Traveling from Gainesville Regional Airport (GNV) to Lambert-St. Louis International Airport (STL): what you need to know

      • St Louis's timezone is UTC-5, which makes St Louis one hour behind Gainesville.

      • To ensure you get on your GNV to STL flight, leave enough time to check in and drop off your luggage. Arriving two hours ahead of international departures and an hour before domestic flights is the general rule.

      • Traveling during a peak month such as April? School holidays and other high seasons can mean longer lines at security. Play it safe and arrive up to four hours before an international flight and two hours before domestic departures.

      • Consider adding a stopover when booking your ticket from Gainesville Regional Airport to Lambert-St. Louis International Airport. Just deselect 'Direct flights only' to break up your trip, or even explore someplace new along the way. Here's where you can stop between GNV and STL:

        • Hartsfield-Jackson Atlanta International Airport

        • Charlotte Douglas International Airport

        • Austin-Bergstrom International Airport

      How to find the cheapest flights from Gainesville Regional Airport (GNV) to Lambert-St. Louis International Airport (STL)

      • $335 is currently the best price for a one-way Gainesville Regional Airport to Lambert-St. Louis International Airport flight. A return flight starts from $401. These prices can change based on demand.

      • Don't leave things to the last minute. You're more likely to get cheap tickets from GNV to STL if you book ahead. Airlines often offer some amazing early bird discounts.

      • Finding cheap flights from Gainesville Regional Airport to Lambert-St. Louis International Airport is easier if you're flexible with your travel plans. Use the 'Whole month' search function to see the lowest fares across the month and land a great deal.

      • You won't have to check every day to find out if fares have gone down when you set up a Price Alert. We'll notify you the moment there's a change in price on cheap flights from GNV to STL.

      • Choose your ideal arrival and departure times, number of stops and airlines with the filters. Or sort your results by 'Cheapest' to see the best deals on flights from Gainesville Regional Airport to Lambert-St. Louis International Airport.

      Handy information about Gainesville Regional Airport (GNV)

      • You'll find GNV at 3400 Northeast 39th Avenue.

      • 82.41% of flights leaving Gainesville Regional Airport arrive at their destination on schedule. With its strong on-time performance, disruptions are unlikely when taking off from GNV.

      • Gainesville Regional Airport is about 6 kilometers from central Gainesville. If you're catching a cab, ride-sharing or driving from the center, it'll take you 10 minutes or so to arrive, depending on the traffic.

      • You can expect a trip time of roughly 20 minutes on public transport.

      • Need a place to stay before your flight from Gainesville Regional Airport to Lambert-St. Louis International Airport? Check out Hyatt Place Gainesville Downtown. Enjoy a good night's rest here before heading to GNV.

      Arriving at Lambert-St. Louis International Airport (STL)

      Getting from Lambert-St. Louis International Airport (STL) to central St Louis

      • The street address for STL is 10701 Lambert International Blvd..

      • Lambert-St. Louis International Airport to the center of St Louis has a drive time of about 20 minutes. It's approximately 26 kilometers away.

      • It'll take around 35 minutes if you're using public transport.

      When to fly to Lambert-St. Louis International Airport (STL)

      • It's time to plan your dates for your flight from Gainesville Regional Airport to Lambert-St. Louis International Airport. July is the busiest month to head to St Louis. If you want a more low-key vibe, go in April.

      • The warmest month in St Louis is July, with the temperature ranging between 17ºC (63ºF) and 33ºC (91ºF). Lock in your flights from Gainesville Regional Airport to Lambert-St. Louis International Airport in this month if this is the type of weather you enjoy.

      • If you want cooler conditions, look for a cheap ticket from GNV to STL in January. Average temperatures are between -8ºC (18ºF) and 7ºC (45ºF) then.

      Explore more of United States

      • St Louis is easy to fall in love with, but there are so many other corners of United States just waiting to be discovered. Around 418 kilometers north-east of St Louis, a trip to Chicago will keep you on the move. Start with leading sights like Millennium Park, Art Institute of Chicago and LandShark Beer Garden at Navy Pier.

      • If you're interested in discovering another corner of United States, consider Indianapolis, roughly 370 kilometers east of St Louis. The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo are the start of reasons to visit.

      Prices shown on this page are estimated lowest prices only. Found in the last 12 days.