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Cheap flights from Houston George Bush Intercntl. to Panama City

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Flight deals from Houston George Bush Intercntl. to Panama City

Looking for a cheap last-minute deal or the best round-trip flight from Houston George Bush Intercntl. Airport to Panama City? If you want to travel next month, round-trip fares start from $505. Find the lowest prices on one-way and round-trip tickets right here.
Panama City.$457 per passenger.Departing Sat, Aug 22, returning Tue, Aug 25.Round-trip flight with Frontier Airlines and Avianca.Outbound indirect flight with Frontier Airlines, departing from Houston George Bush Intercntl. on Sat, Aug 22, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departing from Panama City Tocumen International on Tue, Aug 25, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $457, select.
Panama City.$484 per passenger.Departing Sat, Oct 17, returning Thu, Oct 29.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Houston George Bush Intercntl. on Sat, Oct 17, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departing from Panama City Tocumen International on Thu, Oct 29, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $484, select.
Panama City.$495 per passenger.Departing Thu, Jul 9, returning Tue, Jul 21.Round-trip flight with Frontier Airlines and Avianca.Outbound indirect flight with Frontier Airlines, departing from Houston George Bush Intercntl. on Thu, Jul 9, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departing from Panama City Tocumen International on Tue, Jul 21, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $495, select.
Panama City.$505 per passenger.Departing Sun, Jun 28, returning Thu, Jul 2.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Houston George Bush Intercntl. on Sun, Jun 28, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departing from Panama City Tocumen International on Thu, Jul 2, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $505, select.
Panama City.$505 per passenger.Departing Mon, Jun 8, returning Wed, Jun 10.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Houston George Bush Intercntl. on Mon, Jun 8, arriving in Panama City Tocumen International.Inbound indirect flight with Delta, departing from Panama City Tocumen International on Wed, Jun 10, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $505, select.
Panama City.$543 per passenger.Departing Wed, Jul 29, returning Mon, Aug 3.Round-trip flight with Frontier Airlines and Avianca.Outbound indirect flight with Frontier Airlines, departing from Houston George Bush Intercntl. on Wed, Jul 29, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departing from Panama City Tocumen International on Mon, Aug 3, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $543, select.
Panama City.$576 per passenger.Departing Wed, Sep 9, returning Wed, Sep 23.Round-trip flight with Frontier Airlines and Copa.Outbound indirect flight with Frontier Airlines, departing from Houston George Bush Intercntl. on Wed, Sep 9, arriving in Panama City Tocumen International.Inbound indirect flight with Copa, departing from Panama City Tocumen International on Wed, Sep 23, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $576, select.
Panama City.$639 per passenger.Departing Wed, May 20, returning Wed, May 27.Round-trip flight with Volaris and Avianca.Outbound indirect flight with Volaris, departing from Houston George Bush Intercntl. on Wed, May 20, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departing from Panama City Tocumen International on Wed, May 27, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $639, select.
Panama City.$643 per passenger.Departing Thu, Jan 21, returning Mon, Jan 25.Round-trip flight with Volaris El Salvador and Copa.Outbound indirect flight with Volaris El Salvador, departing from Houston George Bush Intercntl. on Thu, Jan 21, arriving in Panama City Tocumen International.Inbound indirect flight with Copa, departing from Panama City Tocumen International on Mon, Jan 25, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $643, select.
Panama City.$655 per passenger.Departing Thu, Oct 29, returning Mon, Nov 2.Round-trip flight with Frontier Airlines and Copa.Outbound indirect flight with Frontier Airlines, departing from Houston George Bush Intercntl. on Thu, Oct 29, arriving in Panama City Tocumen International.Inbound indirect flight with Copa, departing from Panama City Tocumen International on Mon, Nov 2, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $655, select.
Panama City.$683 per passenger.Departing Sat, Nov 7, returning Sat, Nov 14.Round-trip flight with Volaris El Salvador and Copa.Outbound indirect flight with Volaris El Salvador, departing from Houston George Bush Intercntl. on Sat, Nov 7, arriving in Panama City Tocumen International.Inbound indirect flight with Copa, departing from Panama City Tocumen International on Sat, Nov 14, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $683, select.
Panama City.$683 per passenger.Departing Tue, May 26, returning Tue, Jun 2.Round-trip flight with Avianca and Copa.Outbound indirect flight with Avianca, departing from Houston George Bush Intercntl. on Tue, May 26, arriving in Panama City Tocumen International.Inbound indirect flight with Copa, departing from Panama City Tocumen International on Tue, Jun 2, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $683, select.
Panama City.$693 per passenger.Departing Mon, Aug 31, returning Sun, Sep 6.Round-trip flight with Frontier Airlines and Avianca.Outbound indirect flight with Frontier Airlines, departing from Houston George Bush Intercntl. on Mon, Aug 31, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departing from Panama City Tocumen International on Sun, Sep 6, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $693, select.
Panama City.$728 per passenger.Departing Mon, May 25, returning Fri, Jul 31.Round-trip flight with Viva and Avianca.Outbound indirect flight with Viva, departing from Houston George Bush Intercntl. on Mon, May 25, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departing from Panama City Tocumen International on Fri, Jul 31, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $728, select.
Panama City.$745 per passenger.Departing Mon, Sep 14, returning Mon, Oct 26.Round-trip flight with Avianca.Outbound indirect flight with Avianca, departing from Houston George Bush Intercntl. on Mon, Sep 14, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departing from Panama City Tocumen International on Mon, Oct 26, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $745, select.
Panama City.$786 per passenger.Departing Tue, Nov 24, returning Thu, Dec 10.Round-trip flight with Volaris El Salvador and Avianca.Outbound indirect flight with Volaris El Salvador, departing from Houston George Bush Intercntl. on Tue, Nov 24, arriving in Panama City Tocumen International.Inbound indirect flight with Avianca, departing from Panama City Tocumen International on Thu, Dec 10, arriving in Houston George Bush Intercntl..Price includes taxes and charges.From $786, select.

Find the cheapest month to fly from Houston George Bush Intercntl. to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Houston George Bush Intercntl. to Panama City flights are currently cheapest in August.
May
from $639
Jun
from $505
Jul
from $495
Aug
from $457
Sep
from $576
Oct
from $484
Nov
from $683
Dec
from $793
Jan
from $643
Feb
from $986
Mar
Find prices
Apr
Find prices

Direct flights from Houston George Bush Intercntl. to Panama City

Alternative Houston George Bush Intercntl. to Panama City routes

Looking for the cheapest, fastest or easiest route from Houston George Bush Intercntl. to Panama City? You could fly into the following airports instead.

Panama City Paitilla

5km from central Panama City
Closest
from $1,553
Search flights

Balboa

5km from central Panama City
from $761
Search flights

Panama City Tocumen International

18km from central Panama City
Cheapest
from $457
Search flights

Houston to Panama City: Flight information

The things to know before you go.
Cheapest flight found$457
Cheapest month to flyAugust
Average flight time4 hrs, 12 mins
Most popular airlineCopa
Average flights per week42

Finding cheap flights from Houston George Bush Intercntl. to Panama City: Frequently asked questions

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.
The best price we found for a round-trip flight from Houston George Bush Intercntl. to Panama City is $457. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
4 hours and 12 minutes is the average flight time from Houston George Bush Intercntl. to Panama City.
Copa and United fly direct from Houston George Bush Intercntl. to Panama City.
There are 42 flights per week flying from Houston George Bush Intercntl. to Panama City, as of May 2026.
The cheapest month to fly from Houston George Bush Intercntl. to Panama City is usually August.
If you're flying from Houston George Bush Intercntl. Airport, the cheapest airport near Panama City is Panama City Tocumen International – which is 17.9 km away from the center of Panama City. We've found flights to this airport from $457.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Houston George Bush Intercntl. Airport to Panama City on Saturday, August 22, 2026.
Yes – the average flight time is 4 hours and 12 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.
In May, the average temperature is usually around 28°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.
Currently, Frontier Airlines and United offer the cheapest flight tickets to Panama City.

Traveling from Houston George Bush Intercontinental Airport (IAH) to Panama City: what you need to know

  • Around 4 hours 25 minutes is how long you can expect to be in the air on a direct flight from Houston George Bush Intercontinental Airport to Panama City.

  • The timezone in Panama City is UTC-5. The city is one hour ahead of Houston, where Houston George Bush Intercontinental Airport is located.

  • The most popular route is from Houston George Bush Intercontinental Airport (IAH) to Panama City Tocumen International Airport (PTY). Take your pick of 19 weekly services between these two airports. If you want to get on your way as soon as possible, the earliest flight from IAH to PTY is the 09:34 United Airlines service. If you prefer to leave later in the day, the final departure is at 14:27 with United Airlines.

  • Give yourself plenty of time to make your IAH to Panama City flight. Generally, it's best to arrive at least two hours before international departures and an hour ahead for domestic flights.

  • You'll likely experience longer queues during popular months like July. Arriving up to four hours ahead of international flights and two hours for domestic departures will give you plenty of time for security and boarding.

  • Start your journey at IAH and travel nonstop to Panama City Tocumen International Airport (PTY). That's where you can expect to land when searching for Houston George Bush Intercontinental Airport to Panama City tickets.

  • Look out for promotions from United Airlines. This carrier operates direct flights from Houston George Bush Intercontinental Airport to Panama City.

  • We make it a breeze to book plane tickets from IAH to Panama City with a stopover. To see your options, deselect 'Direct flights only.' Then, select a flight with a stop long enough to explore your chosen city. Top stopovers include:

    • Bogota El Dorado International Airport (BOG)

    • Cancun International Airport (CUN)

    • Monterrey International Airport (MTY)

  • The journey from central Houston to IAH takes around 1 hour 10 minutes by public transport. If you ride-share, drive or grab a cab, you'll cover the 21 kilometers in 30 minutes or so, depending on traffic conditions.

  • Looking for a hotel near IAH? If you're boarding an early flight from Houston George Bush Intercontinental Airport to Panama City, these stays will get you from your pillow to the plane in no time:

  • 79% of flights that take off from Houston George Bush Intercontinental Airport arrive at their destination on time.

  • IAH's address is 16930 JFK Boulevard.

How to find the cheapest flights from Houston George Bush Intercontinental Airport (IAH) to Panama City

  • The lowest price we've found for a one-way Houston George Bush Intercontinental Airport to Panama City flight is $209. The cheapest price for a return flight is $457. Bear in mind fares can change due to demand at the time of booking.

  • To find cheap flights from IAH to Panama City, book as early as possible. Airlines generally offer lower prices when tickets first go on sale.

  • If you're willing to be flexible with your trip dates, take advantage of the 'Whole month' tool. It'll show you the cheapest price across each month when looking for your Houston George Bush Intercontinental Airport to Panama City ticket.

  • You don't need to check every day to find out if fares have dropped when you set up a Price Alert. We'll update you the moment there's an even better deal on cheap flights from IAH to Panama City.

  • Choose your preferred departure and arrival times, airlines and number of stops with our filters. Then, sort the results for your flight from Houston George Bush Intercontinental Airport to Panama City by 'Cheapest,' 'Fastest' or 'Best.'

Airports in Panama City

Panama City Tocumen International Airport (PTY)

  • Panama City Tocumen International Airport (PTY) to the center of Panama City takes around 35 minutes by car. The center is roughly 24 kilometers away.

  • Getting to the center on public transport takes around 50 minutes.

  • Book a hotel close to PTY if you're coming in on a late flight from Houston George Bush Intercontinental Airport to Panama City. Pick one of these options and make your first night all about catching up on rest:

  • For the lowest price, book your vehicle from Panama City Tocumen International Airport about three weeks in advance of your flight from IAH to Panama City.

Panama Pacifico International Airport (BLB)

  • Central Panama City is located around 6 kilometers from Panama Pacifico International Airport (BLB). Once your flight from Houston George Bush Intercontinental Airport to Panama City has landed and you've made your way through the terminal, the drive should take about 10 minutes.

  • The trip will take roughly 20 minutes on public transport.

  • Place the 'Do not disturb' sign on your door and relax at a hotel close to BLB. Here are a few options where you can check in after your IAH to Panama City flight:

  • Snap up the best price by securing your ride from BLB one week in advance. You can also expect to have a wider selection of vehicles.

Best time to go to Panama City

  • It's time to figure out your dates for your flight from Houston George Bush Intercontinental Airport to Panama City. January is the most popular month to travel to Panama City. If you want a more low-key vibe, go in September.

  • Book a Houston George Bush Intercontinental Airport to Panama City plane ticket with a departure in March if you want to visit the city during its warmest month. Expect temperatures to range from 21ºC (70ºF) to 32ºC (90ºF).

  • For cooler conditions, look for a cheap ticket from IAH to Panama City in January when temperatures average between 22ºC (72ºF) and 31ºC (88ºF).

More about Panama City

  • Start your Panama City trip off on the right foot by choosing the ideal place to stay. After booking your flight from Houston George Bush Intercontinental Airport to Panama City, explore our selection of accommodation options including:

  • There are so many things to see and do in this city it can be hard to know where to begin. Metropolitan Cathedral (Catedral Metropolitan), Casco Viejo and Independence Square are major attractions which should be on any good Panama City itinerary.

Explore more of Panama

  • You've visited Panama City, now it's time to explore other corners of Panama. Travel about 322 kilometers west to David to tick off its leading sights. From Museo Antropológico y Etnográfico Dr. Roberto De La Guardia to Raptors To The Rescue and Unachi Botanical garden, you'll have a packed itinerary ahead.

  • Another major destination in Panama, Santiago de Veraguas is located about 193 kilometers southwest of Panama City. Be sure to visit highlights including Santiago the Apostle Cathedral, Santiago de Veraguas.

More travel options

Plan the rest of your trip from Houston to Panama City

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.