Cheap flights from Madrid to St Louis

Compare Madrid to St Louis flight deals

Find the cheapest month or even day of the year to fly to St Louis

Book the best St Louis fare with no extra fees

Flight deals from Madrid to St Louis

Looking for a cheap last-minute deal or the best round-trip flight from Madrid Airport to St Louis Airport? If you want to travel next month, round-trip fares start from $883. Find the lowest prices on one-way and round-trip tickets right here.

St Louis.$690 per passenger.Departing Sat, Sep 26, returning Sat, Oct 17.Round-trip flight with Ryanair and Frontier Airlines.Outbound indirect flight with Ryanair, departing from Madrid on Sat, Sep 26, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departing from St Louis on Sat, Oct 17, arriving in Madrid.Price includes taxes and charges.From $690, select.

St Louis.$726 per passenger.Departing Wed, Oct 7, returning Wed, Oct 14.Round-trip flight with Ryanair and Frontier Airlines.Outbound indirect flight with Ryanair, departing from Madrid on Wed, Oct 7, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departing from St Louis on Wed, Oct 14, arriving in Madrid.Price includes taxes and charges.From $726, select.

St Louis.$739 per passenger.Departing Thu, Jul 23, returning Tue, Jul 28.Round-trip flight with Iberia Express and Frontier Airlines.Outbound indirect flight with Iberia Express, departing from Madrid on Thu, Jul 23, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departing from St Louis on Tue, Jul 28, arriving in Madrid.Price includes taxes and charges.From $739, select.

St Louis.$766 per passenger.Departing Tue, Aug 25, returning Mon, Sep 21.Round-trip flight with TAP Air Portugal and Frontier Airlines.Outbound indirect flight with TAP Air Portugal, departing from Madrid on Tue, Aug 25, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departing from St Louis on Mon, Sep 21, arriving in Madrid.Price includes taxes and charges.From $766, select.

St Louis.$766 per passenger.Departing Wed, Mar 3, returning Thu, Mar 11.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Madrid on Wed, Mar 3, arriving in St Louis.Inbound indirect flight with Delta, departing from St Louis on Thu, Mar 11, arriving in Madrid.Price includes taxes and charges.From $766, select.

St Louis.$786 per passenger.Departing Tue, Sep 8, returning Tue, Sep 22.Round-trip flight with WestJet and Frontier Airlines.Outbound indirect flight with WestJet, departing from Madrid on Tue, Sep 8, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departing from St Louis on Tue, Sep 22, arriving in Madrid.Price includes taxes and charges.From $786, select.

St Louis.$823 per passenger.Departing Mon, Oct 19, returning Mon, Nov 23.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Madrid on Mon, Oct 19, arriving in St Louis.Inbound indirect flight with Delta, departing from St Louis on Mon, Nov 23, arriving in Madrid.Price includes taxes and charges.From $823, select.

St Louis.$827 per passenger.Departing Thu, Apr 1, returning Thu, Apr 15.Round-trip flight with KLM and Air France.Outbound indirect flight with KLM, departing from Madrid on Thu, Apr 1, arriving in St Louis.Inbound indirect flight with Air France, departing from St Louis on Thu, Apr 15, arriving in Madrid.Price includes taxes and charges.From $827, select.

St Louis.$865 per passenger.Departing Tue, Nov 3, returning Sun, Nov 8.Round-trip flight with Wizz Air UK and Lufthansa.Outbound indirect flight with Wizz Air UK, departing from Madrid on Tue, Nov 3, arriving in St Louis.Inbound indirect flight with Lufthansa, departing from St Louis on Sun, Nov 8, arriving in Madrid.Price includes taxes and charges.From $865, select.

St Louis.$869 per passenger.Departing Sat, Sep 12, returning Fri, Nov 6.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Madrid on Sat, Sep 12, arriving in St Louis.Inbound indirect flight with Delta, departing from St Louis on Fri, Nov 6, arriving in Madrid.Price includes taxes and charges.From $869, select.

St Louis.$883 per passenger.Departing Thu, Aug 6, returning Tue, Aug 11.Round-trip flight with Iberia Express and Frontier Airlines.Outbound indirect flight with Iberia Express, departing from Madrid on Thu, Aug 6, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departing from St Louis on Tue, Aug 11, arriving in Madrid.Price includes taxes and charges.From $883, select.

St Louis.$916 per passenger.Departing Thu, Jul 23, returning Wed, Aug 5.Round-trip flight with Ryanair and Frontier Airlines.Outbound indirect flight with Ryanair, departing from Madrid on Thu, Jul 23, arriving in St Louis.Inbound indirect flight with Frontier Airlines, departing from St Louis on Wed, Aug 5, arriving in Madrid.Price includes taxes and charges.From $916, select.

St Louis.$934 per passenger.Departing Sat, May 8, returning Sat, May 29.Round-trip flight with Air Canada.Outbound indirect flight with Air Canada, departing from Madrid on Sat, May 8, arriving in St Louis.Inbound indirect flight with Air Canada, departing from St Louis on Sat, May 29, arriving in Madrid.Price includes taxes and charges.From $934, select.

St Louis.$1,014 per passenger.Departing Wed, Jun 9, returning Sun, Jun 13.Round-trip flight with Lufthansa.Outbound indirect flight with Lufthansa, departing from Madrid on Wed, Jun 9, arriving in St Louis.Inbound indirect flight with Lufthansa, departing from St Louis on Sun, Jun 13, arriving in Madrid.Price includes taxes and charges.From $1,014, select.

St Louis.$1,042 per passenger.Departing Fri, Aug 7, returning Sun, Dec 13.Round-trip flight with Ryanair and Air Canada.Outbound indirect flight with Ryanair, departing from Madrid on Fri, Aug 7, arriving in St Louis.Inbound indirect flight with Air Canada, departing from St Louis on Sun, Dec 13, arriving in Madrid.Price includes taxes and charges.From $1,042, select.

St Louis.$1,057 per passenger.Departing Sat, Oct 17, returning Sat, Jan 2.Round-trip flight with KLM and Air France.Outbound indirect flight with KLM, departing from Madrid on Sat, Oct 17, arriving in St Louis.Inbound indirect flight with Air France, departing from St Louis on Sat, Jan 2, arriving in Madrid.Price includes taxes and charges.From $1,057, select.

Find the cheapest month to fly from Madrid to St Louis

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Madrid to St Louis flights are currently cheapest in October.

Jul

Aug

Sep

Oct

Nov

Dec

Jan

Feb

Mar

Apr

May

Jun

Madrid to St Louis: Alternative routes

Compare routes from Madrid to St Louis below. You may find an airport to fly into that's cheaper, faster, or easier than St Louis.

St Louis

20km from central St Louis

ClosestCheapest

from $690

Search flights

Belleville

32km from central St Louis

Search flights

Madrid to St Louis: Flight information

The things to know before you go.

Cheapest flight found	$690
Cheapest month to fly	September

Finding cheap flights from Madrid to St Louis: Frequently asked questions

How much are round-trip flights from Madrid to St Louis?

The best price we found for a round-trip flight from Madrid to St Louis is $690. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Madrid to St Louis?

Currently, there are no airlines that fly direct from Madrid to St Louis. But we found flights with one or more stops from $690.

How many flights are there a week from Madrid to St Louis?

There are no flights flying from Madrid to St Louis, as of July 2026.

When is the cheapest time to fly from Madrid to St Louis?

The cheapest month to fly from Madrid to St Louis is usually September.

Which upcoming date is cheapest to fly from Madrid Airport to St Louis Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Madrid Airport to St Louis Airport on Saturday, September 26, 2026.

Can I get a direct flight from Madrid Airport to St Louis Airport?

No airlines currently offer direct flights between Madrid Airport and St Louis Airport. Most routes have one or more stops.

How can I find the best flight deal to St Louis?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to St Louis but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to St Louis?

We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to St Louis is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly with from Madrid Airport to St Louis?

Currently, Ryanair offers the cheapest flight tickets to St Louis.

Flying from Madrid Airport (MAD) to St Louis Airport (STL): what you need to know

St Louis's timezone is UTC-6, which makes St Louis seven hours behind Madrid.
For a stress-free journey, arrive at the airport two hours ahead of international flights and one hour before domestic departures. This way, you'll have plenty of time to board your MAD to STL flight.
You can expect longer lines in popular months such as July. Arriving up to four hours ahead of international flights and two hours for a domestic departure is a smart move.
If you want to include a stop along the way, simply uncheck 'Direct flights only' when searching for your ticket from Madrid Airport to St Louis Airport. These are the top stopovers between MAD and STL:
- Chicago O'Hare International Airport
- New York Newark Airport
- Boston Logan International Airport

Handy information about Madrid Airport (MAD)

Of all flights departing from Madrid Airport, 77% arrive as scheduled at their destination.
Madrid Airport is around 13 kilometers from central Madrid. If you're catching a cab, ride-sharing or driving from the center, it'll take you 20 minutes or so to arrive, depending on the traffic.
Catching public transport? You can expect a journey time of around 30 minutes.
Have an early flight from Madrid Airport to St Louis Airport? Avoid the last-minute rush to the terminal (and get some extra shut-eye) by picking one of these stays near MAD:

Arriving at St Louis Airport (STL)

The last thing you want is a long journey to your hotel if you're landing late on a Madrid Airport to St Louis Airport flight. Stay at one of these accommodation options near STL instead:
Go wherever you want, whenever you want with a St Louis Airport rental car. Pick up your wheels from Hertz, Budget or Alamo and discover more of St Louis and beyond.
Reserving your ride from St Louis Airport about one week ahead increases your chances of getting a good deal.

When to fly to St Louis Airport (STL)

The quietest month for a flight from Madrid Airport to St Louis Airport is March, while July is the most popular. Choose the ideal time to go to St Louis based on whether you prefer a laid-back vibe or a more bustling atmosphere.
Lock in your flight from Madrid Airport to St Louis Airport for July if you'd like to explore St Louis during its warmest month. Expect temperatures of between 17ºC (63ºF) and 33ºC (91ºF).
January sees average temperatures of between -7ºC (19ºF) and 8ºC (46ºF). Look for cheap tickets from MAD to STL around that time if you'd rather travel in cooler conditions.

Explore more of the United States

St Louis has loads to offer, but there are so many other parts of the United States just waiting to be discovered. About 418 kilometers north-east of St Louis, a visit to Chicago will keep your itinerary busy. Start with popular sights like Millennium Park, Art Institute of Chicago and Willis Tower.
Around 370 kilometers east of St Louis, Indianapolis is another essential stop in the United States. Start your sightseeing at Lucas Oil Stadium, Eiteljorg Museum and The Children's Museum of Indianapolis.