Cheap flights from Milwaukee General Mitchell to Santa Ana John Wayne

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Compare Milwaukee General Mitchell to Santa Ana John Wayne flight deals

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Flight deals from Milwaukee General Mitchell to Santa Ana John Wayne

Looking for a cheap last-minute deal or the best round-trip flight from Milwaukee General Mitchell Airport to Santa Ana John Wayne Airport? If you want to travel next month, round-trip fares start from $376. Find the lowest prices on one-way and round-trip tickets right here.

Santa Ana.$376 per passenger.Departing Wed, Sep 16, returning Tue, Sep 22.Round-trip flight with United.Outbound indirect flight with United, departing from Milwaukee General Mitchell on Wed, Sep 16, arriving in Santa Ana John Wayne.Inbound indirect flight with United, departing from Santa Ana John Wayne on Tue, Sep 22, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $376, select.

Santa Ana.$377 per passenger.Departing Sat, Nov 7, returning Sat, Nov 14.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Milwaukee General Mitchell on Sat, Nov 7, arriving in Santa Ana John Wayne.Inbound indirect flight with Delta, departing from Santa Ana John Wayne on Sat, Nov 14, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $377, select.

Santa Ana.$431 per passenger.Departing Thu, Oct 22, returning Mon, Oct 26.Round-trip flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departing from Milwaukee General Mitchell on Thu, Oct 22, arriving in Santa Ana John Wayne.Inbound indirect flight with Southwest Airlines, departing from Santa Ana John Wayne on Mon, Oct 26, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $431, select.

Santa Ana.$449 per passenger.Departing Fri, Feb 5, returning Sun, Feb 7.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Milwaukee General Mitchell on Fri, Feb 5, arriving in Santa Ana John Wayne.Inbound indirect flight with Delta, departing from Santa Ana John Wayne on Sun, Feb 7, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $449, select.

Santa Ana.$478 per passenger.Departing Mon, Dec 21, returning Wed, Dec 23.Round-trip flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departing from Milwaukee General Mitchell on Mon, Dec 21, arriving in Santa Ana John Wayne.Inbound indirect flight with Southwest Airlines, departing from Santa Ana John Wayne on Wed, Dec 23, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $478, select.

Santa Ana.$503 per passenger.Departing Tue, Mar 2, returning Sat, Mar 6.Round-trip flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departing from Milwaukee General Mitchell on Tue, Mar 2, arriving in Santa Ana John Wayne.Inbound indirect flight with Southwest Airlines, departing from Santa Ana John Wayne on Sat, Mar 6, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $503, select.

Santa Ana.$516 per passenger.Departing Fri, Dec 18, returning Sun, Jan 17.Round-trip flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departing from Milwaukee General Mitchell on Fri, Dec 18, arriving in Santa Ana John Wayne.Inbound indirect flight with Southwest Airlines, departing from Santa Ana John Wayne on Sun, Jan 17, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $516, select.

Santa Ana.$569 per passenger.Departing Sun, Jan 10, returning Mon, Jan 18.Round-trip flight with United.Outbound indirect flight with United, departing from Milwaukee General Mitchell on Sun, Jan 10, arriving in Santa Ana John Wayne.Inbound indirect flight with United, departing from Santa Ana John Wayne on Mon, Jan 18, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $569, select.

Santa Ana.$607 per passenger.Departing Mon, Aug 31, returning Fri, Sep 4.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Milwaukee General Mitchell on Mon, Aug 31, arriving in Santa Ana John Wayne.Inbound indirect flight with Delta, departing from Santa Ana John Wayne on Fri, Sep 4, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $607, select.

Santa Ana.$874 per passenger.Departing Thu, Aug 20, returning Sun, Aug 23.Round-trip flight with Frontier Airlines.Outbound indirect flight with Frontier Airlines, departing from Milwaukee General Mitchell on Thu, Aug 20, arriving in Santa Ana John Wayne.Inbound indirect flight with Frontier Airlines, departing from Santa Ana John Wayne on Sun, Aug 23, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $874, select.

Santa Ana.$886 per passenger.Departing Fri, Jul 2, returning Wed, Jul 7.Round-trip flight with United.Outbound indirect flight with United, departing from Milwaukee General Mitchell on Fri, Jul 2, arriving in Santa Ana John Wayne.Inbound indirect flight with United, departing from Santa Ana John Wayne on Wed, Jul 7, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $886, select.

Santa Ana.$9,797 per passenger.Departing Sat, Sep 26, returning Sat, Oct 3.Round-trip flight with Alaska Airlines.Outbound indirect flight with Alaska Airlines, departing from Milwaukee General Mitchell on Sat, Sep 26, arriving in Santa Ana John Wayne.Inbound indirect flight with Alaska Airlines, departing from Santa Ana John Wayne on Sat, Oct 3, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $9,797, select.

Santa Ana.$18,974 per passenger.Departing Thu, Oct 29, returning Sun, Nov 1.Round-trip flight with Alaska Airlines.Outbound indirect flight with Alaska Airlines, departing from Milwaukee General Mitchell on Thu, Oct 29, arriving in Santa Ana John Wayne.Inbound indirect flight with Alaska Airlines, departing from Santa Ana John Wayne on Sun, Nov 1, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $18,974, select.

Santa Ana.$19,002 per passenger.Departing Sat, Feb 27, returning Wed, Mar 10.Round-trip flight with Alaska Airlines.Outbound indirect flight with Alaska Airlines, departing from Milwaukee General Mitchell on Sat, Feb 27, arriving in Santa Ana John Wayne.Inbound indirect flight with Alaska Airlines, departing from Santa Ana John Wayne on Wed, Mar 10, arriving in Milwaukee General Mitchell.Price includes taxes and charges.From $19,002, select.

Find the cheapest month to fly from Milwaukee General Mitchell to Santa Ana John Wayne

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Milwaukee General Mitchell to Santa Ana John Wayne flights are currently cheapest in September.

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Milwaukee General Mitchell to Santa Ana John Wayne: Alternative routes

Compare routes from Milwaukee General Mitchell to Santa Ana below. You may find an airport to fly into that's cheaper, faster, or easier than Santa Ana John Wayne.

Milwaukee to Santa Ana: Flight information

The things to know before you go.

Cheapest flight found	$376
Cheapest month to fly	September

Finding cheap flights from Milwaukee General Mitchell to Santa Ana John Wayne: Frequently asked questions

How much are round-trip flights from Milwaukee General Mitchell to Santa Ana John Wayne?

The best price we found for a round-trip flight from Milwaukee General Mitchell to Santa Ana John Wayne is $376. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Milwaukee General Mitchell to Santa Ana John Wayne?

Currently, there are no airlines that fly direct from Milwaukee General Mitchell to Santa Ana John Wayne. But we found flights with one or more stops from $376.

How many flights are there a week from Milwaukee General Mitchell to Santa Ana John Wayne?

There are no flights flying from Milwaukee General Mitchell to Santa Ana John Wayne, as of August 2026.

When is the cheapest time to fly from Milwaukee General Mitchell to Santa Ana John Wayne?

The cheapest month to fly from Milwaukee General Mitchell to Santa Ana John Wayne is usually September.

Which upcoming date is cheapest to fly from Milwaukee General Mitchell Airport to Santa Ana John Wayne Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Milwaukee General Mitchell Airport to Santa Ana John Wayne Airport on Wednesday, September 16, 2026.

Can I get a direct flight from Milwaukee General Mitchell Airport to Santa Ana John Wayne Airport?

No airlines currently offer direct flights between Milwaukee General Mitchell Airport and Santa Ana John Wayne Airport. Most routes have one or more stops.

How can I find the best flight deal to Santa Ana John Wayne?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santa Ana John Wayne but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Santa Ana?

We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Santa Ana is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly with from Milwaukee General Mitchell Airport to Santa Ana John Wayne?

Currently, United offers the cheapest flight tickets to Santa Ana John Wayne.

Flying from Milwaukee General Mitchell Airport (MKE) to Santa Ana John Wayne Airport (SNA): what you need to know

Santa Ana's timezone is UTC-8, which makes Santa Ana two hours behind Milwaukee.
Your MKE to SNA flight won't wait if you're late, so be at the airport on time. Arrive up to one hour in advance for domestic flights and two hours ahead when you're traveling internationally.
Traveling during a peak time like June? Public holidays and other high seasons can result in longer lines and delays at airport checkpoints. Play it safe and arrive up to four hours ahead of an international flight and two hours before domestic departures.
We make it a cinch to book a flight with a stopover. To see all your options for tickets from Milwaukee General Mitchell Airport to Santa Ana John Wayne Airport, deselect 'Direct flights only.' Then, choose a flight offering a stop long enough to tour your chosen city. Some great stopovers between MKE and SNA include:
- Denver International Airport
- Phoenix Sky Harbor Airport
- Harry Reid International Airport

Handy information about Milwaukee General Mitchell Airport (MKE)

The address for MKE is 5300 S. Howell Avenue.
76% of flights leaving from Milwaukee General Mitchell Airport reach their destination on schedule.
To reach Milwaukee General Mitchell Airport from central Milwaukee, it'll take around 20 minutes if you're going by car. Of course, this depends on traffic conditions. It's approximately 16 kilometers from the airport to the city center.
Taking public transport? You can expect a journey time of around 40 minutes.
Get your break off to a leisurely start by staying near MKE. Whether you're taking an early flight from Milwaukee General Mitchell Airport to Santa Ana John Wayne Airport or just don't want to be rushed, these stays have you covered:

Arriving at Santa Ana John Wayne Airport (SNA)

The last thing you need is a lengthy journey to your hotel if you're landing late on a Milwaukee General Mitchell Airport to Santa Ana John Wayne Airport flight. Reserve one of these accommodation options near SNA instead:
Pick up a Santa Ana John Wayne Airport rental car and explore Santa Ana and beyond with your own set of wheels. Thrifty, Dollar and Green Motion are top providers to choose from here.
Reserving your ride from Santa Ana John Wayne Airport about three weeks in advance boosts your odds of scoring a great price.

When to fly to Santa Ana John Wayne Airport (SNA)

It's time to pick your dates for your flight from Milwaukee General Mitchell Airport to Santa Ana John Wayne Airport. July is the most popular month to head to Santa Ana. If you'd like a more laid-back vibe, go in March.
Before locking in your flight from Milwaukee General Mitchell Airport to Santa Ana John Wayne Airport, think about the type of weather you like. August is the warmest month in Santa Ana, with temperatures ranging from 16ºC (61ºF) to 32ºC (90ºF).
If you like traveling in cooler conditions, look for a cheap ticket from MKE to SNA in January. Average temperatures are between 6ºC (43ºF) and 22ºC (72ºF) then.

Explore more of the United States

Los Angeles is just one of the many places in the United States waiting to be discovered once you've seen Santa Ana. Around 48 kilometers away to the north-west, its best attractions include Hollywood Sign, Universal Studios Hollywood and Hollywood Bowl.
If you're eager to discover another well-known destination in the United States, consider San Diego, about 129 kilometers south-east of Santa Ana. San Diego Zoo, San Diego Balboa Park and USS Midway Museum are the start of reasons to visit.