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Cheap flights from Louisville Muhammad Ali International to San Francisco International

Compare Louisville Muhammad Ali International to San Francisco International flight deals

Find the cheapest month or even day of the year to fly to San Francisco International

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Flight deals from Louisville Muhammad Ali International to San Francisco International

Looking for a cheap last-minute deal or the best round-trip flight from Louisville Muhammad Ali International Airport to San Francisco International Airport? If you want to travel next month, round-trip fares start from $314. Find the lowest prices on one-way and round-trip tickets right here.
San Francisco.$298 per passenger.Departing Fri, Sep 4, returning Mon, Sep 7.Round-trip flight with Breeze Airways.Outbound direct flight with Breeze Airways departing from Louisville Muhammad Ali International on Fri, Sep 4, arriving in San Francisco International.Inbound direct flight with Breeze Airways departing from San Francisco International on Mon, Sep 7, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $298, select.
San Francisco.$303 per passenger.Departing Mon, Oct 19, returning Mon, Oct 26.Round-trip flight with Breeze Airways.Outbound direct flight with Breeze Airways departing from Louisville Muhammad Ali International on Mon, Oct 19, arriving in San Francisco International.Inbound direct flight with Breeze Airways departing from San Francisco International on Mon, Oct 26, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $303, select.
San Francisco.$314 per passenger.Departing Mon, Jun 8, returning Fri, Jun 12.Round-trip flight with Breeze Airways.Outbound direct flight with Breeze Airways departing from Louisville Muhammad Ali International on Mon, Jun 8, arriving in San Francisco International.Inbound direct flight with Breeze Airways departing from San Francisco International on Fri, Jun 12, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $314, select.
San Francisco.$318 per passenger.Departing Fri, May 29, returning Mon, Jun 1.Round-trip flight with Breeze Airways.Outbound direct flight with Breeze Airways departing from Louisville Muhammad Ali International on Fri, May 29, arriving in San Francisco International.Inbound direct flight with Breeze Airways departing from San Francisco International on Mon, Jun 1, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $318, select.
San Francisco.$367 per passenger.Departing Fri, Jul 3, returning Fri, Jul 10.Round-trip flight with Breeze Airways.Outbound direct flight with Breeze Airways departing from Louisville Muhammad Ali International on Fri, Jul 3, arriving in San Francisco International.Inbound direct flight with Breeze Airways departing from San Francisco International on Fri, Jul 10, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $367, select.
San Francisco.$368 per passenger.Departing Mon, May 25, returning Fri, May 29.Round-trip flight with Breeze Airways.Outbound direct flight with Breeze Airways departing from Louisville Muhammad Ali International on Mon, May 25, arriving in San Francisco International.Inbound direct flight with Breeze Airways departing from San Francisco International on Fri, May 29, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $368, select.
San Francisco.$386 per passenger.Departing Wed, Aug 5, returning Mon, Aug 10.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Louisville Muhammad Ali International on Wed, Aug 5, arriving in San Francisco International.Inbound indirect flight with Delta, departing from San Francisco International on Mon, Aug 10, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $386, select.
San Francisco.$387 per passenger.Departing Mon, Jun 22, returning Mon, Jul 6.Round-trip flight with Breeze Airways.Outbound direct flight with Breeze Airways departing from Louisville Muhammad Ali International on Mon, Jun 22, arriving in San Francisco International.Inbound direct flight with Breeze Airways departing from San Francisco International on Mon, Jul 6, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $387, select.
San Francisco.$388 per passenger.Departing Fri, Jul 17, returning Fri, Sep 11.Round-trip flight with Breeze Airways.Outbound direct flight with Breeze Airways departing from Louisville Muhammad Ali International on Fri, Jul 17, arriving in San Francisco International.Inbound direct flight with Breeze Airways departing from San Francisco International on Fri, Sep 11, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $388, select.
San Francisco.$390 per passenger.Departing Tue, Oct 20, returning Tue, Nov 3.Round-trip flight with United.Outbound indirect flight with United, departing from Louisville Muhammad Ali International on Tue, Oct 20, arriving in San Francisco International.Inbound indirect flight with United, departing from San Francisco International on Tue, Nov 3, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $390, select.
San Francisco.$392 per passenger.Departing Mon, Sep 28, returning Fri, Oct 2.Round-trip flight with Breeze Airways.Outbound direct flight with Breeze Airways departing from Louisville Muhammad Ali International on Mon, Sep 28, arriving in San Francisco International.Inbound direct flight with Breeze Airways departing from San Francisco International on Fri, Oct 2, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $392, select.
San Francisco.$393 per passenger.Departing Sat, Aug 29, returning Fri, Sep 4.Round-trip flight with Breeze Airways.Outbound indirect flight with Breeze Airways, departing from Louisville Muhammad Ali International on Sat, Aug 29, arriving in San Francisco International.Inbound indirect flight with Breeze Airways, departing from San Francisco International on Fri, Sep 4, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $393, select.
San Francisco.$428 per passenger.Departing Sun, Nov 1, returning Sat, Nov 7.Round-trip flight with United.Outbound indirect flight with United, departing from Louisville Muhammad Ali International on Sun, Nov 1, arriving in San Francisco International.Inbound indirect flight with United, departing from San Francisco International on Sat, Nov 7, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $428, select.
San Francisco.$438 per passenger.Departing Fri, Nov 27, returning Mon, Nov 30.Round-trip flight with Breeze Airways.Outbound direct flight with Breeze Airways departing from Louisville Muhammad Ali International on Fri, Nov 27, arriving in San Francisco International.Inbound direct flight with Breeze Airways departing from San Francisco International on Mon, Nov 30, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $438, select.
San Francisco.$608 per passenger.Departing Sat, Dec 26, returning Wed, Dec 30.Round-trip flight with Southwest Airlines.Outbound indirect flight with Southwest Airlines, departing from Louisville Muhammad Ali International on Sat, Dec 26, arriving in San Francisco International.Inbound indirect flight with Southwest Airlines, departing from San Francisco International on Wed, Dec 30, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $608, select.
San Francisco.$766 per passenger.Departing Mon, Dec 28, returning Mon, Jan 11.Round-trip flight with United.Outbound indirect flight with United, departing from Louisville Muhammad Ali International on Mon, Dec 28, arriving in San Francisco International.Inbound indirect flight with United, departing from San Francisco International on Mon, Jan 11, arriving in Louisville Muhammad Ali International.Price includes taxes and charges.From $766, select.

Find the cheapest month to fly from Louisville Muhammad Ali International to San Francisco International

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Louisville Muhammad Ali International to San Francisco International flights are currently cheapest in September.
May
from $368
Jun
from $314
Jul
from $367
Aug
from $386
Sep
from $298
Oct
from $303
Nov
from $428
Dec
from $608
Jan
Find prices
Feb
Find prices
Mar
Find prices
Apr
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Direct flights from Louisville Muhammad Ali International to San Francisco International

Louisville Muhammad Ali International to San Francisco International: Alternative routes

Compare routes from Louisville Muhammad Ali International to San Francisco below. You may find an airport to fly into that's cheaper, faster, or easier than San Francisco International.

San Francisco International

18km from central San Francisco
ClosestCheapest
from $297
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Oakland Metropolitan Oak

19km from central San Francisco
from $408
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San Carlos

33km from central San Francisco
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Concord

40km from central San Francisco
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San Jose International

63km from central San Francisco
from $435
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San Jose Reid-Hillview

72km from central San Francisco
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Santa Rosa

89km from central San Francisco
from $567
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Louisville to San Francisco: Flight information

The things to know before you go.
Cheapest flight found$298
Cheapest month to flySeptember
Average flight time5 hrs, 12 mins
Most popular airlineBreeze Airways
Average flights per week3

Finding cheap flights from Louisville Muhammad Ali International to San Francisco International: Frequently asked questions

The best price we found for a round-trip flight from Louisville Muhammad Ali International to San Francisco International is $298. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
5 hours and 12 minutes is the average flight time from Louisville Muhammad Ali International to San Francisco International.
Breeze Airways flies direct from Louisville Muhammad Ali International to San Francisco International.
There are 3 flights per week flying from Louisville Muhammad Ali International to San Francisco International, as of May 2026.
The cheapest month to fly from Louisville Muhammad Ali International to San Francisco International is usually September.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Louisville Muhammad Ali International Airport to San Francisco International Airport on Friday, September 4, 2026.
Yes – the average flight time is 5 hours and 12 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to San Francisco International but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to San Francisco is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Breeze Airways offers the cheapest flight tickets to San Francisco International.

Flying from Louisville International Airport-Standiford Field (SDF) to San Francisco International Airport (SFO): what you need to know

  • Take a direct flight from Louisville International Airport-Standiford Field to San Francisco International Airport and you'll be traveling for an average of 5 hours 10 minutes.

  • San Francisco's timezone is UTC-7, making San Francisco three hours behind Louisville.

  • To ensure you catch your SDF to SFO flight, leave enough time to check in and find your gate. Arriving two hours before international departures and one hour before domestic flights is the general travel rule.

  • You'll likely experience longer lines during popular months such as July. Arriving up to four hours in advance for an international flight and two hours for domestic departures will give you ample time for security and boarding.

  • Traveling to San Francisco (and then seeing more of United States!) is easy with Breeze Airways. This popular airline offers direct flights from Louisville International Airport-Standiford Field to San Francisco International Airport.

  • Breeze Airways has the highest passenger demand on this route.

  • We make it easy to book a flight with a stopover. To see your options for tickets from Louisville International Airport-Standiford Field to San Francisco International Airport, uncheck 'Direct flights only.' Then, pick a flight offering a stop long enough to visit your chosen city. Stopovers between SDF and SFO include:

    • Denver International Airport

    • Los Angeles International Airport

    • Harry Reid Airport (formerly McCarran Airport)

How to find the cheapest flights from Louisville International Airport-Standiford Field (SDF) to San Francisco International Airport (SFO)

  • The cheapest price we've seen for a one-way Louisville International Airport-Standiford Field to San Francisco International Airport flight is $123. A return ticket is currently $298. Depending on the availability when you book, these fares may change.

  • Score cheap tickets from SDF to SFO by booking at least ten months ahead. According to our research, that's the sweet spot for picking up a bargain.

  • September is the cheapest month for flights from Louisville International Airport-Standiford Field to San Francisco International Airport. If you want to travel at a different time of year, the 'Whole month' tool will give you the lowest prices for each month.

  • Save time searching for cheap flights from SDF to SFO by setting up a Price Alert. We'll send you an email or push notification on the app when a new low fare is offered.

  • Discover the ideal flight for you with the help of the filters. To see the 'Best,' 'Fastest' or 'Cheapest' flights from Louisville International Airport-Standiford Field to San Francisco International Airport, use the 'Sort by' function. You can also filter by airline, departure and arrival times, and number of stops.

Handy information about Louisville International Airport-Standiford Field (SDF)

  • You'll find SDF at 600 Terminal Drive.

  • Of the departures from Louisville International Airport-Standiford Field, 77.69% land on schedule at their destination.

  • Central Louisville to Louisville International Airport-Standiford Field is approximately 23 kilometers. Depending on traffic, it'll take about 25 minutes to get there if you're driving, ride-sharing or catching a cab.

  • The trip on public transport usually takes 2 hours 40 minutes.

  • Get your vacation off to a leisurely start by staying near SDF. Whether you're catching an early flight from Louisville International Airport-Standiford Field to San Francisco International Airport or want to avoid feeling rushed, these stays are the answer:

Arriving at San Francisco International Airport (SFO)

Getting from San Francisco International Airport (SFO) to central San Francisco

  • From San Francisco International Airport, San Francisco is approximately 21 kilometers away. It takes around 20 minutes to drive to the center.

  • If you're taking public transport, expect a journey of about 45 minutes.

When to fly to San Francisco International Airport (SFO)

  • It's time to plan your travel dates for your flight from Louisville International Airport-Standiford Field to San Francisco International Airport. August is the busiest month to head to San Francisco. If you want a more low-key vibe, go in February.

  • Lock in your flight from Louisville International Airport-Standiford Field to San Francisco International Airport for September if you want to explore San Francisco during its warmest month. You can expect temperatures of between 12ºC (54ºF) and 22ºC (72ºF).

  • If you'd rather travel in cooler conditions, look for a cheap ticket from SDF to SFO in January. Temperatures average between 6ºC (43ºF) and 16ºC (61ºF) then.

Explore more of United States

  • You've seen San Francisco, now it's time to discover other corners of United States. Travel around 64 kilometers south-east to San Jose to tick off its top attractions. From Winchester Mystery House to Rosicrucian Egyptian Museum and San Jose Museum of Art, you'll have a full itinerary ahead.

  • Around 257 kilometers south-east of San Francisco, Fresno is another essential stop in United States. Experience the best of this destination with a visit to Forestiere Underground Gardens, Fresno Chaffee Zoo and Shinzen Japanese Garden.

More travel options

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.