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Cheap flights from San Francisco International to Santo Domingo Las Americas

Compare San Francisco International to Santo Domingo Las Americas flight deals

Find the cheapest month or even day of the year to fly to Santo Domingo Las Americas

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Flight deals from San Francisco International to Santo Domingo Las Americas

Looking for a cheap last-minute deal or the best round-trip flight from San Francisco International Airport to Santo Domingo Las Americas Airport? If you want to travel next month, round-trip fares start from $766. Find the lowest prices on one-way and round-trip tickets right here.
Santo Domingo.$506 per passenger.Departing Wed, Oct 14, returning Wed, Oct 21.Round-trip flight with Copa.Outbound indirect flight with Copa, departing from San Francisco International on Wed, Oct 14, arriving in Santo Domingo Las Americas.Inbound indirect flight with Copa, departing from Santo Domingo Las Americas on Wed, Oct 21, arriving in San Francisco International.Price includes taxes and charges.From $506, select.
Santo Domingo.$507 per passenger.Departing Wed, Sep 23, returning Wed, Sep 30.Round-trip flight with Copa.Outbound indirect flight with Copa, departing from San Francisco International on Wed, Sep 23, arriving in Santo Domingo Las Americas.Inbound indirect flight with Copa, departing from Santo Domingo Las Americas on Wed, Sep 30, arriving in San Francisco International.Price includes taxes and charges.From $507, select.
Santo Domingo.$527 per passenger.Departing Thu, Sep 24, returning Thu, Oct 1.Round-trip flight with Copa.Outbound indirect flight with Copa, departing from San Francisco International on Thu, Sep 24, arriving in Santo Domingo Las Americas.Inbound indirect flight with Copa, departing from Santo Domingo Las Americas on Thu, Oct 1, arriving in San Francisco International.Price includes taxes and charges.From $527, select.
Santo Domingo.$530 per passenger.Departing Sun, Aug 23, returning Sun, Aug 30.Round-trip flight with Copa.Outbound indirect flight with Copa, departing from San Francisco International on Sun, Aug 23, arriving in Santo Domingo Las Americas.Inbound indirect flight with Copa, departing from Santo Domingo Las Americas on Sun, Aug 30, arriving in San Francisco International.Price includes taxes and charges.From $530, select.
Santo Domingo.$547 per passenger.Departing Sat, Jan 23, returning Sat, Jan 30.Round-trip flight with Copa.Outbound indirect flight with Copa, departing from San Francisco International on Sat, Jan 23, arriving in Santo Domingo Las Americas.Inbound indirect flight with Copa, departing from Santo Domingo Las Americas on Sat, Jan 30, arriving in San Francisco International.Price includes taxes and charges.From $547, select.
Santo Domingo.$607 per passenger.Departing Wed, Jul 22, returning Mon, Jul 27.Round-trip flight with Frontier Airlines and Arajet.Outbound indirect flight with Frontier Airlines, departing from San Francisco International on Wed, Jul 22, arriving in Santo Domingo Las Americas.Inbound indirect flight with Arajet, departing from Santo Domingo Las Americas on Mon, Jul 27, arriving in San Francisco International.Price includes taxes and charges.From $607, select.
Santo Domingo.$629 per passenger.Departing Tue, Jul 7, returning Thu, Aug 13.Round-trip flight with Copa.Outbound indirect flight with Copa, departing from San Francisco International on Tue, Jul 7, arriving in Santo Domingo Las Americas.Inbound indirect flight with Copa, departing from Santo Domingo Las Americas on Thu, Aug 13, arriving in San Francisco International.Price includes taxes and charges.From $629, select.
Santo Domingo.$676 per passenger.Departing Sun, Jun 21, returning Wed, Jul 1.Round-trip flight with Frontier Airlines and Arajet.Outbound indirect flight with Frontier Airlines, departing from San Francisco International on Sun, Jun 21, arriving in Santo Domingo Las Americas.Inbound indirect flight with Arajet, departing from Santo Domingo Las Americas on Wed, Jul 1, arriving in San Francisco International.Price includes taxes and charges.From $676, select.
Santo Domingo.$697 per passenger.Departing Mon, May 25, returning Tue, Jun 2.Round-trip flight with Frontier Airlines and Arajet.Outbound indirect flight with Frontier Airlines, departing from San Francisco International on Mon, May 25, arriving in Santo Domingo Las Americas.Inbound indirect flight with Arajet, departing from Santo Domingo Las Americas on Tue, Jun 2, arriving in San Francisco International.Price includes taxes and charges.From $697, select.
Santo Domingo.$713 per passenger.Departing Mon, Nov 23, returning Mon, Nov 30.Round-trip flight with Copa.Outbound indirect flight with Copa, departing from San Francisco International on Mon, Nov 23, arriving in Santo Domingo Las Americas.Inbound indirect flight with Copa, departing from Santo Domingo Las Americas on Mon, Nov 30, arriving in San Francisco International.Price includes taxes and charges.From $713, select.
Santo Domingo.$766 per passenger.Departing Fri, Jun 5, returning Fri, Jun 12.Round-trip flight with Frontier Airlines and Arajet.Outbound indirect flight with Frontier Airlines, departing from San Francisco International on Fri, Jun 5, arriving in Santo Domingo Las Americas.Inbound indirect flight with Arajet, departing from Santo Domingo Las Americas on Fri, Jun 12, arriving in San Francisco International.Price includes taxes and charges.From $766, select.
Santo Domingo.$1,016 per passenger.Departing Fri, May 22, returning Tue, May 26.Round-trip flight with jetBlue.Outbound indirect flight with jetBlue, departing from San Francisco International on Fri, May 22, arriving in Santo Domingo Las Americas.Inbound indirect flight with jetBlue, departing from Santo Domingo Las Americas on Tue, May 26, arriving in San Francisco International.Price includes taxes and charges.From $1,016, select.
Santo Domingo.$1,245 per passenger.Departing Wed, Dec 23, returning Wed, Dec 30.Round-trip flight with jetBlue and Arajet.Outbound indirect flight with jetBlue, departing from San Francisco International on Wed, Dec 23, arriving in Santo Domingo Las Americas.Inbound indirect flight with Arajet, departing from Santo Domingo Las Americas on Wed, Dec 30, arriving in San Francisco International.Price includes taxes and charges.From $1,245, select.
Santo Domingo.$1,380 per passenger.Departing Fri, Dec 18, returning Mon, Jan 4.Round-trip flight with Alaska Airlines and Arajet.Outbound indirect flight with Alaska Airlines, departing from San Francisco International on Fri, Dec 18, arriving in Santo Domingo Las Americas.Inbound indirect flight with Arajet, departing from Santo Domingo Las Americas on Mon, Jan 4, arriving in San Francisco International.Price includes taxes and charges.From $1,380, select.

Find the cheapest month to fly from San Francisco International to Santo Domingo Las Americas

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like San Francisco International to Santo Domingo Las Americas flights are currently cheapest in October.
May
from $1,016
Jun
from $766
Jul
from $607
Aug
from $530
Sep
from $507
Oct
from $506
Nov
from $713
Dec
from $1,245
Jan
from $547
Feb
Find prices
Mar
Find prices
Apr
Find prices

San Francisco International to Santo Domingo Las Americas: Alternative routes

Compare routes from San Francisco International to Santo Domingo below. You may find an airport to fly into that's cheaper, faster, or easier than Santo Domingo Las Americas.

La Isabela International

15km from central Santo Domingo
Closest
Search flights

Santo Domingo Las Americas

23km from central Santo Domingo
Cheapest
from $506
Search flights

Samana

90km from central Santo Domingo
Search flights

San Francisco to Santo Domingo: Flight information

The things to know before you go.
Cheapest flight found$506
Cheapest month to flyOctober

Finding cheap flights from San Francisco International to Santo Domingo Las Americas: Frequently asked questions

The best price we found for a round-trip flight from San Francisco International to Santo Domingo Las Americas is $506. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from San Francisco International to Santo Domingo Las Americas. But we found flights with one or more stops from $506.
There are no flights flying from San Francisco International to Santo Domingo Las Americas, as of May 2026.
The cheapest month to fly from San Francisco International to Santo Domingo Las Americas is usually October.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from San Francisco International Airport to Santo Domingo Las Americas Airport on Wednesday, October 14, 2026.
No airlines currently offer direct flights between San Francisco International Airport and Santo Domingo Las Americas Airport. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo Las Americas but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Copa offers the cheapest flight tickets to Santo Domingo Las Americas.

Flying from San Francisco International Airport (SFO) to Las Americas International Airport (SDQ): what you need to know

  • The timezone in Santo Domingo is UTC-4, which is three hours ahead of San Francisco.

  • Your SFO to SDQ flight won't wait if you're late, so don't forget to check in on time. Arrive up to one hour in advance for domestic flights and two hours ahead when you're flying internationally.

  • During popular months such as August, you'll want to get to the airport earlier than usual. Plan to arrive two hours before a domestic departure and four hours ahead of an international flight when you fly during peak periods in general.

  • Think about adding a stopover when booking your ticket from San Francisco International Airport to Las Americas International Airport. Simply uncheck 'Direct flights only' to break up your journey, or visit a new city along the way. Here's where you can stop between SFO and SDQ:

    • Miami International Airport

    • Hartsfield-Jackson Atlanta International Airport

    • Newark Liberty International Airport

How to find the cheapest flights from San Francisco International Airport (SFO) to Las Americas International Airport (SDQ)

  • The cheapest price we've seen for a one-way San Francisco International Airport to Las Americas International Airport flight is $266. A return fare right now is $506. Depending on the availability and when you book, these fares could change.

  • It's usually best to book as early as possible if you want to get cheap tickets from SFO to SDQ. That's because airlines change prices based on demand, which tends to rise closer to departure.

  • If you're flexible with your travel dates, use the 'Whole month' search tool. It'll find the cheapest price across every month when searching for your flight from San Francisco International Airport to Las Americas International Airport.

  • Never miss a deal on cheap flights from SFO to SDQ by creating a Price Alert. We'll send you an email or notification through the app when a special offer becomes available.

  • Tailor your flights using filters. Pick your preferred departure and arrival times, total journey duration and airlines. You can also sort the results by 'Best,' 'Cheapest' or 'Fastest' flights from San Francisco International Airport to Las Americas International Airport.

Handy information about San Francisco International Airport (SFO)

  • When it comes to the on-time performance of San Francisco International Airport, data shows 77.36% of flights stick to their scheduled arrival time.

  • Central San Francisco to San Francisco International Airport is around 21 kilometers. Depending on traffic, it'll take about 20 minutes to get there if you're catching a cab, ride-sharing or driving.

  • The journey on public transport takes roughly 45 minutes.

  • Looking for a convenient hotel close to SFO? If you're catching an early flight from San Francisco International Airport to Las Americas International Airport, these accommodation options will have you sleeping moments from check-in:

Arriving at Las Americas International Airport (SDQ)

Getting from Las Americas International Airport (SDQ) to central Santo Domingo

  • Las Americas International Airport to the center of Santo Domingo has a drive time of around 30 minutes. It's approximately 32 kilometers away.

When to fly to Las Americas International Airport (SDQ)

  • The quietest month for a flight from San Francisco International Airport to Las Americas International Airport is May, while January is the most popular. Choose the best time to visit Santo Domingo based on whether you prefer a bustling atmosphere or a more laid-back vibe.

  • Lock in your flight from San Francisco International Airport to Las Americas International Airport for September if you want to explore Santo Domingo during its warmest month. Expect temperatures of between 23ºC (73ºF) and 33ºC (91ºF).

  • For cooler conditions, search for a cheap ticket from SFO to SDQ in February. Temperatures average between 19ºC (66ºF) and 29ºC (84ºF) then.

Explore more of Dominican Republic

  • Santo Domingo Este is just one of the many places in Dominican Republic waiting to be discovered after you've experienced Santo Domingo. Around 13 kilometers away to the east, well-known attractions include Museo Las Tres Aves, billeteros Park and Abuela Mota Final Resting Place.

  • If you're eager to discover another great destination in Dominican Republic, consider San Pedro de Macorís, about 64 kilometers east of Santo Domingo. El Parquecito, Patrimonio arquitectónico de la ciudad de San Pedro de Macoris and Museo Cultural San Pedro are key highlights.

More travel options

Plan the rest of your trip from San Francisco to Santo Domingo

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.