Cheap flights from San Francisco International to Santiago

Compare San Francisco International to Santiago flight deals

Find the cheapest month or even day of the year to fly to Santiago

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Flight deals from San Francisco International to Santiago

Looking for a cheap last-minute deal or the best round-trip flight from San Francisco International Airport to Santiago Airport? If you want to travel next month, round-trip fares start from $846. Find the lowest prices on one-way and round-trip tickets right here.

Santiago.$742 per passenger.Departing Tue, Jul 21, returning Fri, Jul 31.Round-trip flight with Frontier Airlines and jetBlue.Outbound indirect flight with Frontier Airlines, departing from San Francisco International on Tue, Jul 21, arriving in Santiago.Inbound indirect flight with jetBlue, departing from Santiago on Fri, Jul 31, arriving in San Francisco International.Price includes taxes and charges.From $742, select.

Santiago.$745 per passenger.Departing Sun, Jun 14, returning Mon, Jul 6.Round-trip flight with Copa.Outbound indirect flight with Copa, departing from San Francisco International on Sun, Jun 14, arriving in Santiago.Inbound indirect flight with Copa, departing from Santiago on Mon, Jul 6, arriving in San Francisco International.Price includes taxes and charges.From $745, select.

Santiago.$749 per passenger.Departing Sat, Jul 18, returning Sat, Aug 15.Round-trip flight with American Airlines.Outbound indirect flight with American Airlines, departing from San Francisco International on Sat, Jul 18, arriving in Santiago.Inbound indirect flight with American Airlines, departing from Santiago on Sat, Aug 15, arriving in San Francisco International.Price includes taxes and charges.From $749, select.

Santiago.$796 per passenger.Departing Sun, Dec 6, returning Mon, Jan 11.Round-trip flight with Copa.Outbound indirect flight with Copa, departing from San Francisco International on Sun, Dec 6, arriving in Santiago.Inbound indirect flight with Copa, departing from Santiago on Mon, Jan 11, arriving in San Francisco International.Price includes taxes and charges.From $796, select.

Santiago.$846 per passenger.Departing Mon, Jun 8, returning Sun, Jun 14.Round-trip flight with Frontier Airlines and jetBlue.Outbound indirect flight with Frontier Airlines, departing from San Francisco International on Mon, Jun 8, arriving in Santiago.Inbound indirect flight with jetBlue, departing from Santiago on Sun, Jun 14, arriving in San Francisco International.Price includes taxes and charges.From $846, select.

Santiago.$871 per passenger.Departing Mon, Aug 17, returning Fri, Aug 21.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from San Francisco International on Mon, Aug 17, arriving in Santiago.Inbound indirect flight with Delta, departing from Santiago on Fri, Aug 21, arriving in San Francisco International.Price includes taxes and charges.From $871, select.

Santiago.$874 per passenger.Departing Thu, Aug 27, returning Tue, Sep 1.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from San Francisco International on Thu, Aug 27, arriving in Santiago.Inbound indirect flight with Delta, departing from Santiago on Tue, Sep 1, arriving in San Francisco International.Price includes taxes and charges.From $874, select.

Santiago.$904 per passenger.Departing Sun, May 17, returning Tue, Jul 7.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from San Francisco International on Sun, May 17, arriving in Santiago.Inbound indirect flight with Delta, departing from Santiago on Tue, Jul 7, arriving in San Francisco International.Price includes taxes and charges.From $904, select.

Santiago.$999 per passenger.Departing Tue, May 19, returning Sun, May 24.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from San Francisco International on Tue, May 19, arriving in Santiago.Inbound indirect flight with Delta, departing from Santiago on Sun, May 24, arriving in San Francisco International.Price includes taxes and charges.From $999, select.

Santiago.$1,116 per passenger.Departing Thu, Sep 3, returning Mon, Sep 7.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from San Francisco International on Thu, Sep 3, arriving in Santiago.Inbound indirect flight with Delta, departing from Santiago on Mon, Sep 7, arriving in San Francisco International.Price includes taxes and charges.From $1,116, select.

Find the cheapest month to fly from San Francisco International to Santiago

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like San Francisco International to Santiago flights are currently cheapest in July.

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San Francisco International to Santiago: Alternative routes

Compare routes from San Francisco International to Santiago below. You may find an airport to fly into that's cheaper, faster, or easier than Santiago.

Santiago

2km from central Santiago

Closest

from $742

Search flights

Puerto Plata

37km from central Santiago

Cheapest

from $648

Search flights

San Francisco to Santiago: Flight information

The things to know before you go.

Cheapest flight found	$742
Cheapest month to fly	July

Finding cheap flights from San Francisco International to Santiago: Frequently asked questions

How much are round-trip flights from San Francisco International to Santiago?

The best price we found for a round-trip flight from San Francisco International to Santiago is $742. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from San Francisco International to Santiago?

Currently, there are no airlines that fly direct from San Francisco International to Santiago. But we found flights with one or more stops from $742.

How many flights are there a week from San Francisco International to Santiago?

There are no flights flying from San Francisco International to Santiago, as of May 2026.

When is the cheapest time to fly from San Francisco International to Santiago?

The cheapest month to fly from San Francisco International to Santiago is usually July.

Which upcoming date is cheapest to fly from San Francisco International Airport to Santiago Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from San Francisco International Airport to Santiago Airport on Tuesday, July 21, 2026.

Can I get a direct flight from San Francisco International Airport to Santiago Airport?

No airlines currently offer direct flights between San Francisco International Airport and Santiago Airport. Most routes have one or more stops.

How can I find the best flight deal to Santiago?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santiago but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Santiago?

We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Santiago is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly with from San Francisco International Airport to Santiago?

Currently, Frontier Airlines offers the cheapest flight tickets to Santiago.

Traveling from San Francisco International Airport (SFO) to Cibao International Airport (STI): what you need to know

The timezone in Santiago is UTC-4, which is three hours ahead of San Francisco.
Your SFO to STI flight won't wait if you're late, so be at the airport on time. Arrive up to one hour in advance for domestic flights and two hours ahead when you're traveling internationally.
During popular months like August, it's best to get to the airport earlier. Plan to arrive two hours before domestic departures and four hours ahead of an international flight whenever you're flying during peak periods in general.
If you'd like to explore another city along the way, simply deselect 'Direct flights only' when searching for your ticket from San Francisco International Airport to Cibao International Airport. These are the most popular stopovers between SFO and STI:
- Miami International Airport
- John F. Kennedy International Airport
- Newark Liberty International Airport

How to find the cheapest flights from San Francisco International Airport (SFO) to Cibao International Airport (STI)

$394 is currently the best price for a one-way San Francisco International Airport to Cibao International Airport flight. Return flights start at $742. These fares can change based on availability.
To pick up cheap tickets from SFO to STI, book ahead. Airlines generally offer their best fares when flights are first released.
The 'Whole month' search tool shows you the cheapest flights from San Francisco International Airport to Cibao International Airport across every month. It's a great way to find a bargain if your plans aren't set in stone.
Landing cheap flights from SFO to STI is a piece of cake with Price Alerts. All you need to do is set up one of these automatic alerts and we'll get in touch when there's a better deal.
Lock in the perfect flight for you by using the filters. To see the 'Best,' 'Cheapest' or 'Fastest' flights from San Francisco International Airport to Cibao International Airport, use the 'Sort by' tool. You can also filter by arrival and departure times, airline, and number of stops.

Handy information about San Francisco International Airport (SFO)

77.36% of flights taking off from San Francisco International Airport make it to their destination on schedule.
San Francisco International Airport is about 21 kilometers from central San Francisco. If you're driving, ride-sharing or catching a cab from the center, it'll take 20 minutes or so to arrive, depending on the traffic.
You can expect a trip time of roughly 45 minutes on public transport.
Searching for a convenient hotel close to SFO? If you're catching an early flight from San Francisco International Airport to Cibao International Airport, these accommodation options will have you sleeping moments from your check-in counter:

Arriving at Cibao International Airport (STI)

If you're coming in on a late San Francisco International Airport to Cibao International Airport flight, nothing beats the convenience of staying near the terminal. Grab your luggage from the carousel and then be resting not long after at one of these accommodation options near STI:
Pick up a Cibao International Airport rental car and explore Santiago and beyond with your own set of wheels. America, Zezgo Rent a Car and Alamo are leading providers to choose from here.
Lock in the best possible rate by reserving your ride from Cibao International Airport about one week before your travel date.

Getting from Cibao International Airport (STI) to central Santiago

Cibao International Airport is roughly 19 kilometers from central Santiago. The drive time takes about 30 minutes.
It typically takes 1 hour 10 minutes if you're traveling on public transport.

When to fly to Cibao International Airport (STI)

The quietest month for a flight from San Francisco International Airport to Cibao International Airport is May, while August is the most popular. Choose the best time to visit Santiago based on whether you prefer a bustling atmosphere or a more laid-back vibe.
The warmest month in Santiago is August, with the temperature ranging between 21ºC (70ºF) and 33ºC (91ºF). Lock in your flights from San Francisco International Airport to Cibao International Airport in this month if this is the type of weather you like.
January has average temperatures of between 16ºC (61ºF) and 29ºC (84ºF). Look for cheap tickets from SFO to STI sometime around then if you like traveling in cooler conditions.

Explore more of Dominican Republic

You've done Santiago, now it's time to explore other parts of Dominican Republic. Travel about 137 kilometers south-east to Santo Domingo to tick off its top sights. From Alcazar de Colon to National Pantheon (Pantheon Nacional) and National Palace, there's plenty to keep you busy.
Santo Domingo Este is another standout destination in Dominican Republic and is around 145 kilometers south-east of Santiago. No trip is complete without a visit to Museo Las Tres Aves, billeteros Park and Abuela Mota Final Resting Place.