Cheap Flights from Medellin to Panama City

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Flight deals from Medellin to Panama City

Looking for a cheap last-minute deal or the best round-trip flight from Medellin to Panama City? If you want to travel next month, round-trip fares start from $208. Find the lowest prices on one-way and round-trip tickets right here.

Panama City.$186 per passenger.Departing Sat, Jan 30, returning Mon, Mar 1.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Sat, Jan 30, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Mon, Mar 1, arriving in José María Córdova International.Price includes taxes and charges.From $186, select.

Panama City.$190 per passenger.Departing Wed, Nov 18, returning Mon, Nov 23.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Wed, Nov 18, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Mon, Nov 23, arriving in José María Córdova International.Price includes taxes and charges.From $190, select.

Panama City.$196 per passenger.Departing Wed, Apr 7, returning Wed, Apr 14.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Wed, Apr 7, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Wed, Apr 14, arriving in José María Córdova International.Price includes taxes and charges.From $196, select.

Panama City.$200 per passenger.Departing Mon, Feb 15, returning Mon, Feb 22.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Mon, Feb 15, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Mon, Feb 22, arriving in José María Córdova International.Price includes taxes and charges.From $200, select.

Panama City.$200 per passenger.Departing Wed, Jan 20, returning Wed, Jan 27.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Wed, Jan 20, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Wed, Jan 27, arriving in José María Córdova International.Price includes taxes and charges.From $200, select.

Panama City.$202 per passenger.Departing Wed, Mar 24, returning Sun, Mar 28.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Wed, Mar 24, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Sun, Mar 28, arriving in José María Córdova International.Price includes taxes and charges.From $202, select.

Panama City.$202 per passenger.Departing Fri, May 14, returning Mon, May 17.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Fri, May 14, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Mon, May 17, arriving in José María Córdova International.Price includes taxes and charges.From $202, select.

Panama City.$204 per passenger.Departing Sun, Feb 28, returning Wed, Mar 3.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Sun, Feb 28, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Wed, Mar 3, arriving in José María Córdova International.Price includes taxes and charges.From $204, select.

Panama City.$205 per passenger.Departing Wed, Jan 20, returning Sun, Apr 11.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Wed, Jan 20, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Sun, Apr 11, arriving in José María Córdova International.Price includes taxes and charges.From $205, select.

Panama City.$205 per passenger.Departing Fri, Jan 29, returning Mon, Feb 1.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Fri, Jan 29, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Mon, Feb 1, arriving in José María Córdova International.Price includes taxes and charges.From $205, select.

Panama City.$207 per passenger.Departing Mon, Nov 2, returning Fri, Dec 25.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Mon, Nov 2, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Fri, Dec 25, arriving in José María Córdova International.Price includes taxes and charges.From $207, select.

Panama City.$209 per passenger.Departing Wed, Sep 23, returning Mon, Sep 28.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Wed, Sep 23, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Mon, Sep 28, arriving in José María Córdova International.Price includes taxes and charges.From $209, select.

Panama City.$216 per passenger.Departing Sun, Oct 18, returning Sat, Oct 24.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Sun, Oct 18, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Sat, Oct 24, arriving in José María Córdova International.Price includes taxes and charges.From $216, select.

Panama City.$218 per passenger.Departing Wed, Dec 9, returning Sat, Dec 12.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Wed, Dec 9, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Sat, Dec 12, arriving in José María Córdova International.Price includes taxes and charges.From $218, select.

Panama City.$220 per passenger.Departing Wed, Sep 30, returning Sat, Oct 3.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Wed, Sep 30, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Sat, Oct 3, arriving in José María Córdova International.Price includes taxes and charges.From $220, select.

Panama City.$235 per passenger.Departing Fri, Dec 25, returning Fri, Jan 1.Round-trip flight with Wingo.Outbound direct flight with Wingo departing from José María Córdova International on Fri, Dec 25, arriving in Balboa.Inbound direct flight with Wingo departing from Balboa on Fri, Jan 1, arriving in José María Córdova International.Price includes taxes and charges.From $235, select.

Find the cheapest month to fly from Medellin to Panama City

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Medellin to Panama City flights are currently cheapest in November.

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Direct flights from Medellin to Panama City

Alternative Medellin to Panama City routes

Looking for the cheapest, fastest or easiest route from Medellin to Panama City? You could fly into the following airports instead.

Medellin to Panama City: Flight information

The things to know before you go.

Cheapest flight found	$186
Cheapest month to fly	January
Average flight time	1 hr, 25 mins
Most popular airline	Copa
Average flights per week	142

Finding cheap flights from Medellin to Panama City: Frequently asked questions

How many airports are there in Panama City?

There are 3 airports in Panama City: Panama City Paitilla, Balboa and Panama City Tocumen International.

How much are round-trip flights from Medellin to Panama City?

The best price we found for a round-trip flight from Medellin to Panama City is $186. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

How long does it take to fly from Medellin to Panama City?

1 hour and 25 minutes is the average flight time from Medellin to Panama City.

Which airlines fly direct from Medellin to Panama City?

Copa, KLM and United fly direct from Medellin to Panama City.

How many flights are there a week from Medellin to Panama City?

There are 142 flights per week flying from Medellin to Panama City, as of August 2026.

When is the cheapest time to fly from Medellin to Panama City?

The cheapest month to fly from Medellin to Panama City is usually January.

What's the cheapest airport to fly to in Panama City?

If you're flying from Medellin, the cheapest airport near Panama City is Balboa – which is 4.9 km away from the center of Panama City. We've found flights to this airport from $186.

Which upcoming date is cheapest to fly from Medellin to Panama City on?

After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Medellin to Panama City on Saturday, January 30, 2027.

Can I get a direct flight from Medellin to Panama City?

Yes – the average flight time is 1 hour and 25 minutes.

How can I get the best flight deal from Medellin to Panama City?

We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Panama City but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.

When is the best time to book flights to Panama City?

We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Panama City is around 40 days in advance, so don’t leave your flight to the last minute.

What’s the weather like in Panama City?

In August, the average temperature is usually around 27°C. May is typically the warmest month in Panama City, when it usually averages around 29°C. You can expect the least rain in February. The coldest month is October, with temperatures averaging 25°C. The rainiest month is June.

Which is the cheapest airline to fly with from Medellin to Panama City?

The cheapest airline that flies to Panama City is Wingo.

Traveling from Medellin to Panama City: what you need to know

Medellin's main base, Medellin Jose Maria Cordova Airport (MDE), is where many unforgettable trips begin. Explore your departure choices from here for your flight from Medellin to Panama City.
Arrive in Panama City at Panama City Tocumen International Airport (PTY) or Balboa Airport (BLB).
Around 1 hour 25 minutes is how long you'll be in transit on a direct Medellin to Panama City flight.
Panama City's timezone is UTC-5, which is the same as Medellin.
Medellin Jose Maria Cordova Airport (MDE) to Panama City Tocumen International Airport (PTY) is the most traveled route that connects these two cities. There are 55 flights a week to choose from. If you prefer starting your day later, the last flight from Medellin to Panama City is with Copa Airlines at 18:21. Choose the first MDE to PTY departure with Copa Airlines at 05:02 to make the most of your first day in Panama City.
To ensure you catch your Medellin to Panama City flight, allow plenty of time for things like baggage drop and finding your gate. Turning up two hours ahead of international departures and an hour before domestic flights is the general rule to follow.
During popular months like December, it's best to get to the airport earlier. Arrive two hours before domestic departures and four hours ahead for an international flight whenever you're flying during high season in general.

How to find the cheapest flights from Medellin to Panama City

Don't leave things to the last minute. You're more likely to find cheap Medellin to Panama City flights if you book ahead. Airlines often have some excellent early bird deals.
If you can be flexible with your travel plans, use the 'Whole month' search tool. It'll give you the cheapest price in each month when looking for your plane ticket from Medellin to Panama City.
There's no need to check back in every day to find out if fares have dropped when you set up a Price Alert. We'll notify you as soon as a better deal comes up on cheap flights from Medellin to Panama City.
Find a cheap Medellin to Panama City flight with the help of our filters. Select your ideal duration, number of stops and airlines, then sort the results by 'Cheapest' to see the best deals.

Flying from Medellin

Medellin Jose Maria Cordova Airport (MDE)

You can book a direct flight from Medellin to Panama City taking off from Medellin Jose Maria Cordova Airport (MDE). Board your plane at MDE and then land at Panama City Tocumen International Airport (PTY) or Balboa Airport (BLB).
Secure your Medellin to Panama City plane tickets with Copa Airlines. This carrier is a top pick for direct flights from MDE.
We make it a breeze to book a Medellin to Panama City flight with a stopover. To see the options leaving from Medellin Jose Maria Cordova Airport, uncheck 'Direct flights only.' Then, choose a flight that has a stop long enough to see the sights of your chosen city. Major stopovers include:
- Bogota Airport (BOG)
- Cali Airport (CLO)
- Cartagena Airport (CTG)
The journey from central Medellin to MDE takes around 1 hour 15 minutes by public transport. If you ride-share, drive or take a cab, you'll cover the 18 kilometers in 45 minutes or so, depending on traffic conditions.
In search of a convenient hotel near Medellin Jose Maria Cordova Airport? If you've booked an early flight from Medellin to Panama City, these stays will have you moments from check-in:
When it comes to the on-time performance of Medellin Jose Maria Cordova Airport, 76% of flights meet their scheduled arrival time.

Arriving in Panama City

Panama City Tocumen International Airport (PTY)

Panama City Tocumen International Airport (PTY) to central Panama City takes around 35 minutes to reach by car. The center is roughly 18 kilometers away.
If you're taking public transport, expect a journey time of roughly 50 minutes.
Reserve a hotel near PTY if you have a late flight from Medellin to Panama City. Choose one of these options and skip the long transfer:
Get on the fast track to adventure by picking up a Panama City Tocumen International Airport rental car. Grab your wheels from Avis, Dollar or MEX and explore beyond Panama City's main sights.
Lock in the lowest price by booking your ride from Panama City Tocumen International Airport about three weeks in advance of your trip.

Panama City Paitilla Airport (PAC)

Central Panama City is around 5 kilometers from Panama City Paitilla Airport (PAC). Step off your flight from Medellin to Panama City and then keep a lookout for any airport signs that'll help you get to the center.
There are some comfortable places to lay your head close to PAC. Kick back after your Medellin to Panama City flight at any of these perfectly located options:
The quickest way to reach your destination is with a Panama City Paitilla Airport rental car. Grab a set of wheels from Thrifty, Avis or Alamo and make a speedy getaway.
Get the lowest price by reserving your ride from PAC three weeks in advance. You'll also have access to a greater range of vehicles.

Balboa Airport (BLB)

Balboa Airport (BLB) is around 5 kilometers from central Panama City. It'll take you about 10 minutes to get to the city center by cab or ride-share once you've stepped off your flight from Medellin to Panama City.
The journey will take you around 20 minutes when traveling on public transport.
Whether you're searching for a mini just for you or a spacious SUV to fit a group of friends, you'll find the right Balboa Airport rental car for your needs. Browse the range of wheels available from companies such as Sixt, Dollar and Thrifty.
If you're looking for a specific make or model, book your ride from BLB around one week before your flight from Medellin to Panama City. This improves your chances of getting the car you prefer, as well as a better rate.

Best time to go to Panama City

It's time to pick your trip dates for your flight from Medellin to Panama City. July is the most popular month to visit Panama City. If you like a more relaxed atmosphere, go in March.
Book a Medellin to Panama City ticket departing in March if you want to experience the city during its warmest month. You can expect temperatures in Panama City to range from 21ºC (70ºF) to 32ºC (90ºF).
If you want cooler conditions, search for a cheap flight from Medellin to Panama City in January when temperatures average between 22ºC (72ºF) and 31ºC (88ºF).

More about Panama City

Start your Panama City trip off on the right foot by choosing the ideal place to stay. After booking your flight from Medellin to Panama City, explore our range of hotels including:
There are so many things to discover in this city it can be tricky to work out where to start. San Felipe, Metropolitan Cathedral Basilica of Santa Maria the Ancient and Independence Square are highlights which should feature on any well-planned Panama City itinerary.